HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: KIF14 (Q15058)
Kinesin-like protein KIF14
Gene: KIF14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008017 - microtubule binding GO:0016020 - membrane GO:0051301 - cell division
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 1648
+	Hs
		1066645 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		724838 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		728480 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		725166 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		1066471 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		551712 DESP_HUMAN (214-616): 3.69e-13: 75.4: 14.63		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		1066752 MYO5C_HUMAN (194-519): 6.56e-13: 74.5: 9.71		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		155103 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		KIFC3_HUMAN (34-705): 1.19e-161: 514: 25.83
+	Hs
		154970 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		KIF7_HUMAN (353-1504): 1.73e-147: 490: 18.81
+	Hs
		725033 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		KI13B_HUMAN (356-1164): 2.11e-131: 453: 33.45
+	Hs
		231520 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52