Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 29755126
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0046872 - metal ion binding
GO:2001237 - negative regulation of extrinsic apoptotic signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 923
Hs

1 1130
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024