HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 897 Hs			1 758
+	Hs
		497394 TNPO1_HUMAN (2-897): 0: 625: 84.39		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496647 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497032 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		312169 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581954 IMB1_RAT (11-871): 2.73e-84: 291: 17.53		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94177 IMB1_RAT (11-871): 2.73e-84: 291: 17.53		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		1056831 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		127171 IPO5_HUMAN (20-627): 9.22e-15: 81.2: 10.75		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Dm
		973547 XPO2_DROME (4-894): 1.14e-86: 299: 12.82		CPN_DROME (345-756): 7.29e-11: 67.8: 11.17
+	Hs
		127176 IPO5_HUMAN (20-627): 9.22e-15: 81.2: 10.75		MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84