Protein: C2C2L
Phospholipid transfer protein C2CD2L (C2 domain-containing protein 2-like) (C2CD2-like) (Transmembrane protein 24)

Gene: C2C2L, C2CD2L
Organism: Homo sapiens
Interactions: 115
UniProt ID: O14523

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0008526 - phosphatidylinositol transfer activity
GO:0032541 - cortical endoplasmic reticulum
GO:0035091 - phosphatidylinositol binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155424

ICOSL
ICOS ligand

2

1

High-throughput

0.811

High

155455

KPCT
Protein kinase C theta type

2

0

High-throughput

0.770

High

155437

FSHR
Follicle-stimulating hormone receptor

2

1

High-throughput

0.628

High

155498

KCNS3
Delayed-rectifier potassium channel regulatory subunit KCNS3

2

1

High-throughput

0.628

High

155501

PCDC1
Protocadherin alpha-C1

2

13

High-throughput

0.628

High

155506

PCDBG
Protocadherin beta-16

2

11

High-throughput

0.628

High

155519

PCDGG
Protocadherin gamma-B4

2

12

High-throughput

0.628

High

155520

PCDAC
Protocadherin alpha-12

2

10

High-throughput

0.628

High

155523

PCDB7
Protocadherin beta-7

2

10

High-throughput

0.628

High

155525

PCDBB
Protocadherin beta-11

2

10

High-throughput

0.628

High

155531

PCDC2
Protocadherin alpha-C2

2

10

High-throughput

0.628

High

155512

ELOV5
Very long chain fatty acid elongase 5

3

0

High-throughput

0.625

High

155422

TMPS2
Transmembrane protease serine 2

2

1

High-throughput

0.606

High

155433

CXB1
Gap junction beta-1 protein

2

1

High-throughput

0.606

High

155445

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.606

High

155447

CXCR3
C-X-C chemokine receptor type 3

2

1

High-throughput

0.606

High

155499

REEP2
Receptor expression-enhancing protein 2

2

1

High-throughput

0.606

High

155503

REEP4
Receptor expression-enhancing protein 4

2

1

High-throughput

0.606

High

155465

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

0

High-throughput

0.602

High

155488

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.602

High

155493

MRAP2
Melanocortin-2 receptor accessory protein 2

2

0

High-throughput

0.602

High

155516

I20RA
Interleukin-20 receptor subunit alpha

2

0

High-throughput

0.602

High

48435

ESYT2
Extended synaptotagmin-2

1

0

High-throughput

0.586

High

155423

STX7
Syntaxin-7

1

0

High-throughput

0.586

High

155444

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

155429

RASK
GTPase KRas

2

2

High-throughput

0.584

High

140053

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

155434

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

155435

MUC1
Mucin-1

2

0

High-throughput

0.580

High

155438

IL3RA
Interleukin-3 receptor subunit alpha

2

0

High-throughput

0.580

High

155442

OPRM
Mu-type opioid receptor

2

0

High-throughput

0.580

High

155450

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.580

High

155451

CLRN1
Clarin-1

2

0

High-throughput

0.580

High

155463

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

155468

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.580

High

155473

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

155478

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

155483

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.580

High

155484

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

155505

CHODL
Chondrolectin

2

0

High-throughput

0.580

High

155522

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

155476

BTNL3
Butyrophilin-like protein 3

1

0

High-throughput

0.578

High

155430

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

155514

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

2

1

High-throughput

0.553

High

155436

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

1

High-throughput

0.536

High

155486

I17RC
Interleukin-17 receptor C

1

1

High-throughput

0.536

High

155494

ZDH12
Palmitoyltransferase ZDHHC12

1

1

High-throughput

0.536

High

155524

PCDB3
Protocadherin beta-3

1

10

High-throughput

0.536

High

155526

PCDGL
Protocadherin gamma-C4

1

11

High-throughput

0.536

High

155527

PCDGH
Protocadherin gamma-B5

1

12

High-throughput

0.536

High

155528

PCDGE
Protocadherin gamma-B2

1

12

High-throughput

0.536

High

155529

PCDGD
Protocadherin gamma-B1

1

12

High-throughput

0.536

High

155530

PCDA8
Protocadherin alpha-8

1

10

High-throughput

0.536

High

155457

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

0

High-throughput

0.513

High

155462

AVR2B
Activin receptor type-2B

1

0

High-throughput

0.513

High

155470

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

155492

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

155513

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

155474

TMM88
Transmembrane protein 88

1

0

High-throughput

0.493

High

155521

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.493

High

155428

RASN
GTPase NRas

1

2

High-throughput

0.479

High

155454

RHOB
Rho-related GTP-binding protein RhoB

1

8

High-throughput

0.479

High

155456

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

155467

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

155507

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

155439

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

155420

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

155421

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

155431

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

155432

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

155449

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

155452

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

155461

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

155464

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.458

High

155491

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

155497

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

155500

DERL1
Derlin-1

1

0

High-throughput

0.458

High

155502

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

155518

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.458

High

155482

S22AF
Solute carrier family 22 member 15

1

1

High-throughput

0.445

High

155489

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

155446

EAA4
Excitatory amino acid transporter 4

1

0

High-throughput

0.426

High

155440

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.316

High

155458

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

155460

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

155469

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

155508

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

155453

1433G
14-3-3 protein gamma

2

0

High-throughput

0.313

High

155471

UROL1
Uromodulin-like 1

1

0

High-throughput

0.279

Low

155481

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

155485

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

155510

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.279

Low

155515

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

155466

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.269

Low

155427

LERL1
Leptin receptor overlapping transcript-like 1

1

0

High-throughput

0.268

Low

155459

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.268

Low

155479

AMGO1
Amphoterin-induced protein 1

1

0

High-throughput

0.268

Low

155495

ZDH15
Palmitoyltransferase ZDHHC15

1

0

High-throughput

0.268

Low

155511

TM248
Transmembrane protein 248

1

0

High-throughput

0.268

Low

155472

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

155477

CPEB2
Cytoplasmic polyadenylation element-binding protein 2

1

0

Small-scale

0.251

Low

104824

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

155425

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

155426

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

155443

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

155448

EMD
Emerin

1

0

High-throughput

0.249

Low

155475

BRWD3
Bromodomain and WD repeat-containing protein 3

1

0

High-throughput

0.249

Low

155487

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

155490

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

155496

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

155504

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

155509

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

155517

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

155441

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.232

Low

155480

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025