HitPredict

Interactor 1: CPLX1 (O14810)
Complexin-1 (Complexin I) (CPX I) (Synaphin-2)
Gene: CPLX1

Interactor 2: SNP25 (P60880)
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)
Gene: SNAP25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 11832227, 12200427, 21785414, 21785412
Identification Methods x-ray crystallography, pull down, fluorescent resonance energy transfer
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006887 - exocytosis
GO:0007268 - chemical synaptic transmission
GO:0016079 - synaptic vesicle exocytosis
GO:0031201 - SNARE complex
and 2 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 134
Hs

1 206
+ Rn
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024