Protein: TRAD1
TRAF-type zinc finger domain-containing protein 1 (Protein FLN29)

Gene: TRAD1, TRAFD1
Organism: Homo sapiens
Interactions: 74
UniProt ID: O14545

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0008270 - zinc ion binding
GO:0045824 - negative regulation of innate immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

156104

PRKN
E3 ubiquitin-protein ligase parkin

3

1

High-throughput

0.640

High

156146

ACD11
Acyl-CoA dehydrogenase family member 11

2

0

High-throughput

0.602

High

156112

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

2

High-throughput

0.594

High

156175

TRAF6
TNF receptor-associated factor 6

1

11

Small-scale

0.561

High

156115

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

156149

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

156113

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.479

High

156145

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

156107

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

156111

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

156119

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

156125

ZN131
Zinc finger protein 131

1

0

High-throughput

0.458

High

156147

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

156156

RNF31
E3 ubiquitin-protein ligase RNF31

1

0

High-throughput

0.458

High

156163

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.458

High

156170

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.458

High

156171

TES
Testin

1

0

High-throughput

0.458

High

156124

NRAM2
Natural resistance-associated macrophage protein 2

1

1

High-throughput

0.445

High

156108

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.437

High

156109

ISG15
Ubiquitin-like protein ISG15

1

3

Small-scale

0.437

High

156122

BAG6
Large proline-rich protein BAG6

1

3

Small-scale

0.437

High

156137

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.437

High

156165

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

156172

UBQL2
Ubiquilin-2

1

1

High-throughput

0.437

High

836

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

156106

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

156168

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.426

High

156123

NRAM1
Natural resistance-associated macrophage protein 1

1

1

High-throughput

0.407

High

156127

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.407

High

156141

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.407

High

156142

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.407

High

156174

S27A6
Long-chain fatty acid transport protein 6

1

2

High-throughput

0.407

High

156159

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

4

0

High-throughput

0.364

High

156152

ASPM
Abnormal spindle-like microcephaly-associated protein

3

0

Small-scale

0.345

High

156116

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.334

High

156117

ERD21
ER lumen protein-retaining receptor 1

2

0

High-throughput

0.328

High

156143

XKR2
XK-related protein 2

2

0

High-throughput

0.328

High

156162

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

2

0

High-throughput

0.328

High

156164

BTBD1
BTB/POZ domain-containing protein 1

2

0

High-throughput

0.328

High

156121

HD
Huntingtin

2

0

High-throughput

0.317

High

156129

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.279

Low

156131

ILK
Scaffold protein ILK

1

0

High-throughput

0.279

Low

156133

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

156138

AG10B
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

0

High-throughput

0.279

Low

156150

IQCF2
IQ domain-containing protein F2

1

0

High-throughput

0.279

Low

156151

CDK20
Cyclin-dependent kinase 20

1

0

High-throughput

0.279

Low

156158

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.279

Low

156161

BBS4
BBSome complex member BBS4

1

0

High-throughput

0.279

Low

156114

H14
Histone H1.4

1

0

High-throughput

0.269

Low

156110

IGF1R
Insulin-like growth factor 1 receptor

1

0

High-throughput

0.261

Low

156103

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

156105

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

156118

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.249

Low

156120

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

156126

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

156128

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

156130

TF65
Transcription factor p65

1

0

High-throughput

0.249

Low

156132

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

156134

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

156135

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.249

Low

156136

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

156144

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

156153

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

156155

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

156160

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

156166

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

156167

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

156169

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

156173

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

156139

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

156140

ZNT6
Zinc transporter 6

1

0

High-throughput

0.232

Low

156148

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.232

Low

156154

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.232

Low

156157

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025