HitPredict

Interactor 1: PHX2A (O14813)
Paired mesoderm homeobox protein 2A (ARIX1 homeodomain protein) (Aristaless homeobox protein homolog) (Paired-like homeobox 2A)
Gene: PHOX2A

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10644760
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 284 Hs			1 2442
+	Hs
		882150 GSC_HUMAN (34-173): 4.21e-41: 144: 37.82		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1270771 PHX2B_HUMAN (1-186): 3.58e-35: 130: 64.58		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		620186 PAX7_HUMAN (73-268): 5.74e-33: 128: 33.67		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		882125 GSC_HUMAN (34-173): 4.21e-41: 144: 37.82		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		620147 PAX7_HUMAN (73-268): 5.74e-33: 128: 33.67		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		641388 PAX6_HUMAN (37-283): 4.95e-31: 121: 24.70		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70910 PITX2_MOUSE (44-275): 1.28e-31: 121: 24.14		EP300_MOUSE (1-2426): 0: 867: 53.61
+	Dm
		115982 DLL_DROME (19-232): 2.7e-43: 151: 30.63		M9PH39_DROME (480-2357): 0: 829: 35.44
+	Dm
		116025 Q9W1H7_DROME (75-191): 2.15e-34: 125: 47.86		M9PH39_DROME (480-2357): 0: 829: 35.44
+	Hs
		170302 LHX2_HUMAN (23-231): 1.56e-34: 130: 26.54		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		170262 PAX6_HUMAN (37-283): 4.95e-31: 121: 24.70		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		882142 GSC_HUMAN (34-173): 4.21e-41: 144: 37.82		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		839772 LHX2_HUMAN (23-231): 1.56e-34: 130: 26.54		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		839836 LHX2_HUMAN (23-231): 1.56e-34: 130: 26.54		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		620215 PAX7_HUMAN (73-268): 5.74e-33: 128: 33.67		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		839785 LHX2_HUMAN (23-231): 1.56e-34: 130: 26.54		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		641466 PAX6_HUMAN (37-283): 4.95e-31: 121: 24.70		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		620175 PAX7_HUMAN (73-268): 5.74e-33: 128: 33.67		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		641391 PAX6_HUMAN (37-283): 4.95e-31: 121: 24.70		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		203210 PAX6_HUMAN (37-283): 4.95e-31: 121: 24.70		SYNJ1_HUMAN (1984-2407): 1.04e-11: 73.3: 10.86