HitPredict

Interactor 1: PSA7 (O14818)
Proteasome subunit alpha type-7 (Proteasome subunit RC6-1) (Proteasome subunit XAPC7)
Gene: PSMA7

Interactor 2: SEM1 (P60896)
26S proteasome complex subunit SEM1 (26S proteasome complex subunit DSS1) (Deleted in split hand/split foot protein 1) (Split hand/foot deleted protein 1) (Split hand/foot malformation type 1 protein)
Gene: SEM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	18775730, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 70
+	Hs
		656188 PSA5_HUMAN (3-232): 1.08e-94: 279: 35.32		SEM1_HUMAN (1-70): 3.65e-23: 84.7: 100.00
+	Hs
		893526 PSA6_HUMAN (2-236): 1.66e-93: 276: 32.64		SEM1_HUMAN (1-70): 3.65e-23: 84.7: 100.00
+	Hs
		637662 PSA2_HUMAN (3-232): 1.61e-48: 161: 37.87		SEM1_HUMAN (1-70): 3.65e-23: 84.7: 100.00