HitPredict

Interactor 1: PSA7 (O14818)
Proteasome subunit alpha type-7 (Proteasome subunit RC6-1) (Proteasome subunit XAPC7)
Gene: PSMA7

Interactor 2: PSME4 (Q14997)
Proteasome activator complex subunit 4 (Proteasome activator PA200)
Gene: PSME4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BLM10_mid~Proteasome, DUF3437~Proteasome, BLM10_mid~Proteasome_A_N, DUF3437~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 1843
+	Hs
		656228 PSA5_HUMAN (3-232): 1.08e-94: 279: 35.32		PSME4_HUMAN (1-1843): 0: 2463: 100.00
+	Hs
		893671 PSA6_HUMAN (2-236): 1.66e-93: 276: 32.64		PSME4_HUMAN (1-1843): 0: 2463: 100.00
+	Hs
		637420 PSA1_HUMAN (3-244): 5.16e-93: 275: 32.11		PSME4_HUMAN (1-1843): 0: 2463: 100.00
+	Hs
		637689 PSA2_HUMAN (3-232): 1.61e-48: 161: 37.87		PSME4_HUMAN (1-1843): 0: 2463: 100.00
+	Sc
		771369 PSA4_YEAST (2-232): 1.85e-93: 276: 58.55		BLM10_YEAST (74-831): 0: 722: 16.61