Protein: ARG28
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor)

Gene: ARG28, ARHGEF28
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q8N1W1

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0003723 - RNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

213367

ARHG9
Rho guanine nucleotide exchange factor 9

2

12

High-throughput

0.767

High

1254212

ARHGI
Rho guanine nucleotide exchange factor 18

2

17

High-throughput

0.767

High

463644

LYN
Tyrosine-protein kinase Lyn

1

19

High-throughput

0.691

High

728332

AKT1
RAC-alpha serine/threonine-protein kinase

1

12

Small-scale

0.647

High

962258

RHOA
Transforming protein RhoA

1

20

High-throughput

0.647

High

691234

1433T
14-3-3 protein theta

1

20

High-throughput

0.618

High

730045

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.618

High

730758

1433S
14-3-3 protein sigma

1

20

High-throughput

0.618

High

966601

1433G
14-3-3 protein gamma

1

20

High-throughput

0.618

High

971770

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.618

High

990486

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.618

High

1040972

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

13

Small-scale

0.618

High

1049547

1433F
14-3-3 protein eta

1

20

High-throughput

0.618

High

1125898

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

13

Small-scale

0.618

High

1096094

TADBP
TAR DNA-binding protein 43

2

6

Small-scale

0.606

High

1323802

NEK7
Serine/threonine-protein kinase Nek7

1

5

High-throughput

0.594

High

978155

RHOB
Rho-related GTP-binding protein RhoB

1

20

Small-scale

0.590

High

1086375

AKP13
A-kinase anchor protein 13

1

17

High-throughput

0.575

High

772899

MYH9
Myosin-9

1

3

High-throughput

0.515

High

697949

CALR
Calreticulin

1

0

High-throughput

0.493

High

788096

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.493

High

408982

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

775198

FUS
RNA-binding protein FUS

1

1

Small-scale

0.479

High

984192

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

10

High-throughput

0.479

High

1107919

SQSTM
Sequestosome-1

1

6

Small-scale

0.479

High

1227050

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.479

High

1323801

POC1B
POC1 centriolar protein homolog B

1

11

High-throughput

0.479

High

1323805

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1161793

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.458

High

457550

TBB5
Tubulin beta chain

1

5

High-throughput

0.445

High

1323799

DNJB8
DnaJ homolog subfamily B member 8

1

3

High-throughput

0.445

High

1323806

SMC3
Structural maintenance of chromosomes protein 3

1

6

High-throughput

0.445

High

1323807

RUVB1
RuvB-like 1

1

3

High-throughput

0.445

High

1323808

KLK5
Kallikrein-5

1

2

High-throughput

0.445

High

294003

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

139266

UPK2
Uroplakin-2

1

0

High-throughput

0.426

High

859901

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.426

High

634782

GRAH
Granzyme H

1

2

High-throughput

0.407

High

1206056

DYLT4
Dynein light chain Tctex-type 4

1

1

High-throughput

0.407

High

1258503

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.407

High

1323798

POC1A
POC1 centriolar protein homolog A

1

11

High-throughput

0.407

High

1323804

KLK15
Kallikrein-15

1

3

High-throughput

0.407

High

1006271

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.316

High

690044

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.232

Low

889930

VEGFB
Vascular endothelial growth factor B

1

0

High-throughput

0.232

Low

1178847

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.232

Low

1211430

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.232

Low

1323800

F174A
Membrane protein FAM174A

1

0

High-throughput

0.232

Low

1323803

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025