Interactor 1: AIM2 (O14862)
Interferon-inducible protein AIM2 (Absent in melanoma 2)
Gene: AIM2

Interactor 2: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 25665578
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0045087 - innate immune response
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 343
Hs

1 882
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024