HitPredict

Interactor 1: BACH1 (O14867)
Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303)
Gene: BACH1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Hs			1 768
+	Hs
		1042469 BACH2_HUMAN (1-736): 1.68e-129: 406: 29.07		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042881 KLH20_HUMAN (8-333): 1.57e-75: 257: 19.70		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041853 KLH24_HUMAN (2-356): 3.22e-73: 251: 17.36		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Rn
		78189 KLH17_RAT (5-337): 3.91e-69: 241: 16.32		CUL3_RAT (1-768): 0: 951: 99.61
+	Hs
		1041852 KLH17_HUMAN (5-337): 7.33e-69: 240: 16.32		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042768 KLHL3_HUMAN (13-301): 1.33e-69: 240: 19.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		299515 KLH18_HUMAN (6-301): 1.66e-69: 240: 20.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Mm
		1225041 KLHL2_MOUSE (13-301): 1.38e-69: 241: 18.77		CUL3_MOUSE (1-768): 0: 949: 99.48
+	Hs
		307170 KLHL2_HUMAN (13-301): 5.11e-69: 239: 19.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041712 KLH12_HUMAN (14-328): 8.05e-69: 238: 18.50		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042674 KLH28_HUMAN (16-370): 1.36e-66: 232: 15.56		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Dm
		1213852 KLHDB_DROME (8-281): 1.56e-70: 244: 21.94		Q8IP45_DROME (17-768): 0: 868: 69.08
+	Dm
		980063 KELC_DROME (10-282): 3.85e-64: 234: 18.48		Q8IP45_DROME (17-768): 0: 868: 69.08
+	Hs
		1043281 KLHL3_HUMAN (13-301): 1.33e-69: 240: 19.11		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043391 KLH12_HUMAN (14-328): 8.05e-69: 238: 18.50		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Rn
		70072 KLH17_RAT (5-337): 3.91e-69: 241: 16.32		B1WBY1_RAT (17-768): 0: 709: 30.53
+	Hs
		1041022 KLH12_HUMAN (14-328): 8.05e-69: 238: 18.50		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1040975 KEAP1_HUMAN (2-334): 3.05e-66: 232: 18.13		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041317 KEAP1_HUMAN (2-334): 3.05e-66: 232: 18.13		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		299529 KLH18_HUMAN (6-301): 1.66e-69: 240: 20.00		CUL5_HUMAN (25-768): 0: 597: 23.77