HitPredict

Interactor 1: BACH1 (O14867)
Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303)
Gene: BACH1

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	30891497, 35914814
Identification Methods	affinity chromatography technology, two hybrid, two hybrid fragment pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 1102
+	Hs
		1239144 ZBT38_HUMAN (1-516): 7.78e-70: 250: 17.74		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1049290 KEAP1_HUMAN (2-334): 3.05e-66: 232: 18.13		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1241824 ZBT44_HUMAN (18-294): 1.96e-65: 229: 26.96		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273805 KLHL5_HUMAN (1-297): 2.76e-64: 229: 17.28		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273939 KLHL8_HUMAN (2-364): 3.18e-63: 224: 13.17		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1054293 NF2L1_HUMAN (524-624): 2.43e-18: 91.7: 47.53		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		781410 BCL6_HUMAN (16-127): 3.15e-13: 75.1: 38.05		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		157232 BACH1_HUMAN (1-736): 0: 558: 100.00		UBP47_HUMAN (208-737): 3.48e-107: 368: 26.62
+	Hs
		1239143 ZBT38_HUMAN (1-516): 7.78e-70: 250: 17.74		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1120797 KLH12_HUMAN (14-328): 8.05e-69: 238: 18.50		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1049236 KEAP1_HUMAN (2-334): 3.05e-66: 232: 18.13		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05
+	Hs
		1241837 ZBT44_HUMAN (18-294): 1.96e-65: 229: 26.96		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Hs
		64225 KLH20_HUMAN (8-333): 1.57e-75: 257: 19.70		UBP27_HUMAN (187-521): 3.14e-90: 298: 20.05
+	Hs
		781388 BCL6_HUMAN (16-127): 3.15e-13: 75.1: 38.05		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		1081238 NF2L2_HUMAN (524-620): 7.71e-13: 73.9: 42.27		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1081218 NF2L2_HUMAN (524-620): 7.71e-13: 73.9: 42.27		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05