HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21642987
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 437
+	Hs
		157420 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		157449 IFIT3_HUMAN (1-490): 2.07e-117: 355: 100.00		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		456254 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		456204 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		441842 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		441841 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		456279 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		456227 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		174583 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		174562 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Sc
		376753 CDC27_YEAST (28-320): 1.5e-47: 177: 15.05		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Hs
		174849 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Mm
		665754 CTR9_MOUSE (22-254): 4.94e-11: 67.6: 12.08		PABP1_MOUSE (4-361): 4.42e-53: 189: 11.08
+	Sc
		542143 CYC8_YEAST (236-479): 1.68e-16: 84.5: 13.15		RU17_YEAST (3-297): 9.1e-46: 162: 26.58
+	Hs
		174475 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55
+	Sc
		376611 CYC8_YEAST (236-479): 1.68e-16: 84.5: 13.15		PABP_YEAST (2-281): 3.47e-29: 121: 12.15