HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: PHAR4 (Q8IZ21)
Phosphatase and actin regulator 4
Gene: PHACTR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 702
+	Hs
		456288 IFIT1_HUMAN (1-453): 1.03e-86: 276: 42.74		PHAR4_HUMAN (1-702): 3.04e-73: 252: 100.00
+	Hs
		456238 IFIT2_HUMAN (1-444): 1.97e-81: 262: 56.96		PHAR4_HUMAN (1-702): 3.04e-73: 252: 100.00
+	Hs
		672901 CDC27_HUMAN (86-489): 4.89e-27: 117: 11.06		CHD8_HUMAN (71-636): 1.81e-26: 118: 10.56
+	Hs
		103911 G5EA36_HUMAN (99-489): 1.7e-26: 115: 10.91		CHD8_HUMAN (71-636): 1.81e-26: 118: 10.56
+	Hs
		174891 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		MDC1_HUMAN (61-694): 5.38e-15: 81.6: 10.31
+	Hs
		175053 OGT1_HUMAN (8-242): 6e-34: 138: 17.45		KMT2C_HUMAN (51-625): 6.81e-14: 78.1: 9.92
+	Hs
		183137 KDM6A_HUMAN (38-401): 7.2e-34: 138: 10.24		KMT2C_HUMAN (51-625): 6.81e-14: 78.1: 9.92
+	Hs
		150104 UTY_HUMAN (38-372): 8.38e-33: 134: 11.03		KMT2C_HUMAN (51-625): 6.81e-14: 78.1: 9.92
+	Hs
		672833 CDC27_HUMAN (86-489): 4.89e-27: 117: 11.06		MDC1_HUMAN (61-694): 5.38e-15: 81.6: 10.31
+	Hs
		1160977 CTR9_HUMAN (22-254): 2.71e-11: 68.3: 11.67		CHD8_HUMAN (71-636): 1.81e-26: 118: 10.56