HitPredict

Interactor 1: TX1B3 (O14907)
Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1)
Gene: TAX1BP3

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0007266 - Rho protein signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 124 Hs			1 193
+	Hs
		158270 LIN7A_HUMAN (10-123): 4.64e-27: 101: 23.48		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436460 SNX27_HUMAN (16-124): 8.53e-27: 105: 20.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		900824 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925331 PDZ11_HUMAN (3-121): 1.66e-26: 97.7: 22.69		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		925539 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436472 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Mm
		925797 DLG4_MOUSE (11-111): 4.01e-22: 92: 33.33		RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22
+	Hs
		951251 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		894337 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545419 PDZ11_HUMAN (3-121): 1.66e-26: 97.7: 22.69		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		545571 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		892409 PDZ11_HUMAN (3-121): 1.66e-26: 97.7: 22.69		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		892548 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Mm
		1111996 DLG4_MOUSE (11-111): 4.01e-22: 92: 33.33		Q3TLP8_MOUSE (1-193): 3.88e-75: 226: 51.64
+	Hs
		436297 SCRIB_HUMAN (21-108): 1.65e-19: 84.6: 28.09		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		915909 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		545370 SCRIB_HUMAN (21-108): 1.65e-19: 84.6: 28.09		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		120595 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		892367 SCRIB_HUMAN (21-108): 1.65e-19: 84.6: 28.09		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		120433 SCRIB_HUMAN (21-108): 1.65e-19: 84.6: 28.09		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98