HitPredict

Interactor 1: LIN7A (O14910)
Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	24366813
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 540
+	Hs
		1033920 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		1033929 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		158277 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		158271 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		DLG4_HUMAN (66-394): 4.83e-27: 117: 16.02
+	Hs
		1334777 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		1021563 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Mm
		292491 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		DLG1_MOUSE (7-322): 5.28e-28: 120: 17.13
+	Hs
		1021573 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Rn
		677810 LIN7B_RAT (18-214): 2.15e-51: 167: 78.17		DLG4_RAT (66-394): 4.41e-27: 117: 16.02
+	Hs
		942382 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		DLG4_HUMAN (66-394): 4.83e-27: 117: 16.02
+	Hs
		942387 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		DLG4_HUMAN (66-394): 4.83e-27: 117: 16.02
+	Hs
		158256 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		158295 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		INADL_HUMAN (7-369): 2.84e-15: 81.5: 12.73
+	Hs
		280072 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		280082 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		1246435 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		INADL_HUMAN (7-369): 2.84e-15: 81.5: 12.73
+	Hs
		1246444 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		INADL_HUMAN (7-369): 2.84e-15: 81.5: 12.73
+	Dm
		677711 Q9VBY7_DROME (21-210): 3.56e-47: 156: 77.90		DLG1_DROME (119-219): 8.38e-15: 79.9: 33.96
+	Ce
		60959 A5JYY2_CAEEL (25-187): 8.41e-35: 129: 27.98		DLG1_CAEEL (117-199): 3.35e-15: 81: 32.96