HitPredict

Interactor 1: CXL11 (O14625)
C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11)
Gene: CXCL11

Interactor 2: CXL14 (O95715)
C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
Gene: CXCL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005615 - extracellular space GO:0006935 - chemotaxis GO:0007165 - signal transduction GO:0007267 - cell-cell signaling GO:0008009 - chemokine activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 111
+	Hs
		343130 CXL10_HUMAN (1-93): 5.24e-27: 96.3: 31.18		CXL14_HUMAN (1-111): 3e-72: 211: 100.00
+	Hs
		343134 CXCL2_HUMAN (19-91): 1.84e-22: 85.1: 31.51		CXL14_HUMAN (1-111): 3e-72: 211: 100.00
+	Hs
		343139 CXCL5_HUMAN (16-90): 1.53e-21: 83.2: 24.00		CXL14_HUMAN (1-111): 3e-72: 211: 100.00
+	Hs
		343128 CXCL7_HUMAN (24-90): 5.76e-21: 82: 25.37		CXL14_HUMAN (1-111): 3e-72: 211: 100.00
+	Hs
		343147 CXCL9_HUMAN (20-90): 3.14e-20: 80.1: 40.85		CXL14_HUMAN (1-111): 3e-72: 211: 100.00
+	Hs
		343141 SDF1_HUMAN (1-94): 9.99e-20: 77.8: 25.53		CXL14_HUMAN (1-111): 3e-72: 211: 100.00
+	Hs
		343129 PLF4_HUMAN (27-92): 5.86e-18: 73.5: 25.76		CXL14_HUMAN (1-111): 3e-72: 211: 100.00