Protein: CXCL2
C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)]

Gene: CXCL2
Organism: Homo sapiens
Interactions: 29
UniProt ID: P19875

Gene Ontology (top 5):
GO:0002237 - response to molecule of bacterial origin
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006935 - chemotaxis
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

390359

PLF4
Platelet factor 4

1

19

High-throughput

0.716

High

562867

CCL5
C-C motif chemokine 5

1

20

High-throughput

0.716

High

626426

SDF1
Stromal cell-derived factor 1

1

7

High-throughput

0.716

High

141745

CCL21
C-C motif chemokine 21

1

20

High-throughput

0.692

High

158933

CXL11
C-X-C motif chemokine 11

1

18

High-throughput

0.692

High

343134

CXL14
C-X-C motif chemokine 14

1

6

High-throughput

0.692

High

626424

CXCL5
C-X-C motif chemokine 5

1

17

High-throughput

0.692

High

626425

XCL1
Lymphotactin

1

20

High-throughput

0.692

High

626428

CCL11
Eotaxin

1

20

High-throughput

0.692

High

626429

CCL8
C-C motif chemokine 8

1

20

High-throughput

0.692

High

626430

CXCL6
C-X-C motif chemokine 6

1

17

High-throughput

0.692

High

626432

CXCL9
C-X-C motif chemokine 9

1

17

High-throughput

0.692

High

626436

CCL28
C-C motif chemokine 28

1

7

High-throughput

0.692

High

626437

XCL2
Cytokine SCM-1 beta

1

20

High-throughput

0.692

High

480484

GROA
Growth-regulated alpha protein

1

18

High-throughput

0.691

High

626419

CXCL3
C-X-C motif chemokine 3

1

18

High-throughput

0.691

High

518762

IL8
Interleukin-8

1

18

Small-scale

0.618

High

626420

CXCR2
C-X-C chemokine receptor type 2

1

20

Small-scale

0.618

High

626421

DPP4
Dipeptidyl peptidase 4

2

5

Small-scale

0.585

High

626431

TF65
Transcription factor p65

1

15

Small-scale

0.479

High

626422

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.460

High

399268

MMP1
Interstitial collagenase

1

20

Small-scale

0.445

High

575777

MMP9
Matrix metalloproteinase-9

1

20

Small-scale

0.445

High

626423

MMP12
Macrophage metalloelastase

1

20

Small-scale

0.445

High

626434

PI3R5
Phosphoinositide 3-kinase regulatory subunit 5

1

0

High-throughput

0.438

High

626427

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.279

Low

626435

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.279

Low

626438

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

High-throughput

0.279

Low

626433

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025