HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 18423203
Identification Methods protein kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_2, L27~L27, PDZ~PDZ, PDZ~SH3_2, Pkinase~Pkinase, SH3_2~SH3_2
Common GO terms GO:0001953 - negative regulation of cell-matrix adhesion
GO:0004385 - guanylate kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005102 - signaling receptor binding
GO:0005516 - calmodulin binding
and 29 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 926
Hs

1 926
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Dm
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ Hs
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+ Mm
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+ Dm

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Last updated: 15 Jul 2024