HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: MYCL (P12524)
Protein L-Myc (Class E basic helix-loop-helix protein 38) (bHLHe38) (Protein L-Myc-1) (V-myc myelocytomatosis viral oncogene homolog)
Gene: MYCL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 926 Hs			1 364
+	Hs
		159129 CSKP_HUMAN (1-926): 0: 973: 100.00		MYC_HUMAN (1-362): 1e-76: 245: 29.75
+	Hs
		159133 CSKP_HUMAN (1-926): 0: 973: 100.00		MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05
+	Hs
		347313 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		MYC_HUMAN (1-362): 1e-76: 245: 29.75
+	Hs
		347148 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		MYC_HUMAN (1-362): 1e-76: 245: 29.75
+	Hs
		379539 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05
+	Hs
		379041 MARK3_HUMAN (4-669): 7.23e-139: 434: 19.62		MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05
+	Hs
		252905 MARK3_HUMAN (4-669): 7.23e-139: 434: 19.62		MITF_HUMAN (130-362): 9.35e-34: 132: 14.34
+	Hs
		346720 KCC2D_HUMAN (8-312): 3.56e-88: 291: 47.71		MYC_HUMAN (1-362): 1e-76: 245: 29.75
+	Hs
		346719 KCC2G_HUMAN (8-312): 4.57e-83: 280: 46.08		MYC_HUMAN (1-362): 1e-76: 245: 29.75
+	Hs
		380030 KCC2A_HUMAN (8-312): 6.34e-85: 282: 46.08		MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05
+	Dm
		959131 KCC2A_DROME (8-319): 1.39e-83: 280: 45.22		MYC_DROME (112-364): 2.04e-32: 130: 20.16