HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: K1C15 (P19012)
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)
Gene: KRT15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 456
+	Hs
		159854 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1C16_HUMAN (101-418): 1.73e-155: 451: 76.10
+	Hs
		159833 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1C14_HUMAN (103-454): 9.83e-146: 425: 69.58
+	Hs
		160064 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1C26_HUMAN (34-449): 8.17e-142: 415: 49.88
+	Hs
		159853 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1C19_HUMAN (59-414): 3.71e-140: 409: 64.89
+	Hs
		160003 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1H1_HUMAN (99-417): 4.47e-126: 374: 57.81
+	Hs
		159999 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KT33B_HUMAN (99-417): 1.85e-122: 364: 57.19
+	Hs
		160065 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1C25_HUMAN (91-432): 5.62e-120: 359: 57.64
+	Hs
		159813 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT34_HUMAN (99-417): 5.45e-120: 357: 56.56
+	Hs
		160063 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K1C27_HUMAN (45-451): 2.02e-115: 348: 53.11
+	Hs
		159796 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT86_HUMAN (1-417): 8.09e-97: 301: 24.11
+	Hs
		159824 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K2C75_HUMAN (2-429): 1.43e-95: 300: 23.99
+	Hs
		160204 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT82_HUMAN (30-417): 1.47e-86: 275: 27.51
+	Hs
		159814 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT36_HUMAN (6-454): 1.29e-80: 258: 48.61
+	Hs
		160121 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT35_HUMAN (14-417): 3.65e-80: 257: 49.75
+	Hs
		159834 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K2C6A_HUMAN (70-436): 1.05e-77: 253: 24.19