HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: EPHA6 (Q9UF33)
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)
Gene: EPHA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 1036
+	Hs
		160004 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA7_HUMAN (9-1036): 0: 1192: 55.53
+	Hs
		159937 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA5_HUMAN (11-1028): 0: 1177: 56.86
+	Hs
		159938 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA4_HUMAN (15-1036): 0: 1176: 56.88
+	Hs
		159898 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA3_HUMAN (24-1028): 0: 1168: 59.56
+	Hs
		277152 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA6_HUMAN (1-1036): 0: 1301: 100.00
+	Hs
		159900 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHB2_HUMAN (34-1036): 0: 1138: 51.33
+	Hs
		159899 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA8_HUMAN (34-1036): 0: 1095: 52.45
+	Hs
		159897 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA2_HUMAN (6-1036): 0: 1046: 45.57
+	Hs
		277067 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA7_HUMAN (9-1036): 0: 1192: 55.53
+	Hs
		277036 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA5_HUMAN (11-1028): 0: 1177: 56.86
+	Hs
		277037 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA4_HUMAN (15-1036): 0: 1176: 56.88
+	Hs
		277011 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA3_HUMAN (24-1028): 0: 1168: 59.56
+	Hs
		277012 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA8_HUMAN (34-1036): 0: 1095: 52.45
+	Hs
		277010 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA2_HUMAN (6-1036): 0: 1046: 45.57
+	Hs
		159889 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR3_HUMAN (221-960): 3.46e-178: 541: 20.51
+	Hs
		159885 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR2_HUMAN (251-982): 2.91e-159: 492: 20.41
+	Hs
		159864 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		277004 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR3_HUMAN (221-960): 3.46e-178: 541: 20.51
+	Hs
		277002 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR2_HUMAN (251-982): 2.91e-159: 492: 20.41
+	Hs
		276996 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36