HitPredict

Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	33001583, 28007913
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1311 Hs			1 870
+	Hs
		161650 GAK_HUMAN (1-1311): 0: 1191: 100.00		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		882363 TENS3_HUMAN (402-1221): 5.51e-150: 492: 20.28		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		882203 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		1158052 MAST2_HUMAN (4-1261): 5.14e-180: 581: 13.40		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Hs
		882578 TENS1_HUMAN (544-1199): 1.23e-13: 78.4: 12.33		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		890664 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16