Protein: TPC2
Two pore channel protein 2 (Two pore calcium channel protein 2)

Gene: TPC2, TPCN2
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q8NHX9

Gene Ontology (top 5):
GO:0005245 - voltage-gated calcium channel activity
GO:0005262 - calcium channel activity
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1246117

TPC1
Two pore channel protein 1

1

10

Small-scale

0.665

High

150242

AP3D1
AP-3 complex subunit delta-1

2

1

High-throughput

0.628

High

153149

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

2

2

High-throughput

0.628

High

508113

FGFR1
Fibroblast growth factor receptor 1

2

15

High-throughput

0.628

High

926236

VAMP2
Vesicle-associated membrane protein 2

2

2

High-throughput

0.628

High

1079380

VAMP3
Vesicle-associated membrane protein 3

2

2

High-throughput

0.628

High

1127492

WDR44
WD repeat-containing protein 44

2

6

High-throughput

0.628

High

1244167

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

2

3

High-throughput

0.628

High

1246103

ANR27
Ankyrin repeat domain-containing protein 27

2

6

High-throughput

0.628

High

1246112

RAB6B
Ras-related protein Rab-6B

2

7

High-throughput

0.628

High

1246116

DP13A
DCC-interacting protein 13-alpha

2

2

High-throughput

0.628

High

1246097

TPC2
Two pore channel protein 2

1

10

Small-scale

0.618

High

120005

AP3B1
AP-3 complex subunit beta-1

2

0

High-throughput

0.602

High

212941

STX6
Syntaxin-6

2

0

High-throughput

0.602

High

686013

ARRB2
Beta-arrestin-2

2

0

High-throughput

0.602

High

850326

CLCN3
H(+)/Cl(-) exchange transporter 3

2

0

High-throughput

0.602

High

968185

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

0

High-throughput

0.602

High

1139773

RRAGB
Ras-related GTP-binding protein B

2

0

High-throughput

0.602

High

1216746

TPPC5
Trafficking protein particle complex subunit 5

2

0

High-throughput

0.602

High

1218647

DEN6A
Protein DENND6A

2

0

High-throughput

0.602

High

1241461

DGLB
Diacylglycerol lipase-beta

2

0

High-throughput

0.602

High

1242524

CBPC5
Cytosolic carboxypeptidase-like protein 5

2

0

High-throughput

0.602

High

1246104

NFIP1
NEDD4 family-interacting protein 1

2

0

High-throughput

0.602

High

1246107

WDR11
WD repeat-containing protein 11

2

0

High-throughput

0.602

High

1246114

TSR3
18S rRNA aminocarboxypropyltransferase

2

0

High-throughput

0.602

High

1246115

FBX10
F-box only protein 10

2

0

High-throughput

0.602

High

1246118

TPPC8
Trafficking protein particle complex subunit 8

2

0

High-throughput

0.602

High

199598

B4GT5
Beta-1,4-galactosyltransferase 5

2

1

High-throughput

0.574

High

577044

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

2

10

High-throughput

0.574

High

738382

BMR1A
Bone morphogenetic protein receptor type-1A

2

5

High-throughput

0.574

High

1057901

DIP2A
Disco-interacting protein 2 homolog A

2

1

High-throughput

0.574

High

1069025

NOMO1
BOS complex subunit NOMO1

2

1

High-throughput

0.574

High

1125724

ZRAB3
DNA annealing helicase and endonuclease ZRANB3

2

2

High-throughput

0.574

High

1190260

LRP10
Low-density lipoprotein receptor-related protein 10

2

5

High-throughput

0.574

High

1240615

UXS1
UDP-glucuronic acid decarboxylase 1

2

1

High-throughput

0.574

High

1246100

TR19L
Tumor necrosis factor receptor superfamily member 19L

2

1

High-throughput

0.574

High

1246110

PCDH9
Protocadherin-9

2

20

High-throughput

0.574

High

1246111

CD320
CD320 antigen

2

5

High-throughput

0.574

High

1246119

KC1G3
Casein kinase I isoform gamma-3

2

2

High-throughput

0.574

High

722944

ADA1A
Alpha-1A adrenergic receptor

1

1

High-throughput

0.541

High

777056

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.536

High

856277

HXK3
Hexokinase-3

1

1

High-throughput

0.536

High

1246109

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

118370

HAX1
HCLS1-associated protein X-1

1

1

Small-scale

0.523

High

503230

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.513

High

1065076

SNX17
Sorting nexin-17

1

0

High-throughput

0.513

High

1246105

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.513

High

1246106

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.513

High

617000

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

10

High-throughput

0.489

High

935952

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.489

High

1240686

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.489

High

1246099

AP3S1
AP-3 complex subunit sigma-1

1

2

High-throughput

0.489

High

1246108

EHD4
EH domain-containing protein 4

1

2

High-throughput

0.489

High

167982

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.479

High

787528

MTOR
Serine/threonine-protein kinase mTOR

1

2

Small-scale

0.479

High

897576

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

1246098

CERK1
Ceramide kinase

2

0

High-throughput

0.328

High

1246102

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.328

High

1246113

ZDH18
Palmitoyltransferase ZDHHC18

2

0

High-throughput

0.328

High

234033

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.279

Low

1068305

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.279

Low

1160596

TM154
Transmembrane protein 154

1

0

High-throughput

0.279

Low

1246101

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

0

High-throughput

0.279

Low

66880

D11L8
Putative ATP-dependent RNA helicase DDX11-like protein 8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024