HitPredict

Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1311 Hs			1 530
+	Hs
		161615 GAK_HUMAN (1-1311): 0: 1191: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		377817 SIK3_HUMAN (20-1211): 0: 644: 13.46		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		1147696 TENS3_HUMAN (402-1221): 5.51e-150: 492: 20.28		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369277 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		818873 KCC2B_HUMAN (40-430): 6.64e-91: 310: 22.70		RXRG_HUMAN (13-499): 1.71e-119: 361: 22.76
+	Hs
		377305 KCC2B_HUMAN (40-430): 6.64e-91: 310: 22.70		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		1269721 BMP2K_HUMAN (35-311): 2.28e-41: 168: 41.79		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369718 AAK1_HUMAN (28-311): 2.6e-43: 174: 39.09		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370525 BMP2K_HUMAN (35-311): 2.28e-41: 168: 41.79		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487277 PTEN_HUMAN (396-779): 3.71e-100: 327: 24.14		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		274187 STK16_HUMAN (46-316): 3.31e-29: 121: 30.50		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		487772 TENS1_HUMAN (544-1199): 1.23e-13: 78.4: 12.33		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59