Protein: WDR5B
WD repeat-containing protein 5B

Gene: WDR5B
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q86VZ2

Gene Ontology (top 5):
GO:0042393 - histone binding
GO:0048188 - Set1C/COMPASS complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

965071

WDR5
WD repeat-containing protein 5

2

18

Small-scale

0.611

High

1007118

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.609

High

610750

TCPA
T-complex protein 1 subunit alpha

2

20

High-throughput

0.574

High

821436

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.574

High

882014

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.574

High

899463

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.574

High

922457

CLH2
Clathrin heavy chain 2

2

4

High-throughput

0.574

High

1044358

HSF2
Heat shock factor protein 2

2

3

High-throughput

0.574

High

1291937

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

2

High-throughput

0.574

High

1291938

TCPW
T-complex protein 1 subunit zeta-2

2

20

High-throughput

0.574

High

564009

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.494

High

1291946

AT132
Polyamine-transporting ATPase 13A2

1

4

Small-scale

0.494

High

537452

HSP7C
Heat shock cognate 71 kDa protein

1

9

High-throughput

0.489

High

1114921

CUL4A
Cullin-4A

1

20

Small-scale

0.489

High

1115283

CUL4B
Cullin-4B

1

20

Small-scale

0.489

High

1191865

TBB8
Tubulin beta-8 chain

1

11

High-throughput

0.489

High

1245040

TRI65
E3 ubiquitin-protein ligase TRIM65

1

4

High-throughput

0.489

High

1246866

RICTR
Rapamycin-insensitive companion of mTOR

1

3

High-throughput

0.489

High

1259315

TBA1A
Tubulin alpha-1A chain

1

9

High-throughput

0.489

High

1291939

ARHG1
Rho guanine nucleotide exchange factor 1

1

15

High-throughput

0.489

High

1291940

MAGD4
Melanoma-associated antigen D4

1

7

High-throughput

0.489

High

1291941

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.489

High

1291943

TBA1C
Tubulin alpha-1C chain

1

10

High-throughput

0.489

High

1291945

WDR6
tRNA

1

18

High-throughput

0.489

High

1291949

TRM7
tRNA

1

2

High-throughput

0.489

High

1291950

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.489

High

1145487

RBBP5
Retinoblastoma-binding protein 5

1

19

Small-scale

0.445

High

1291942

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

19

Small-scale

0.445

High

1291948

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

14

Small-scale

0.445

High

144291

ACACB
Acetyl-CoA carboxylase 2

1

12

High-throughput

0.437

High

248731

PEPL
Periplakin

1

20

High-throughput

0.437

High

315745

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.437

High

528294

THIO
Thioredoxin

1

7

High-throughput

0.437

High

587723

DESP
Desmoplakin

1

18

High-throughput

0.437

High

637611

FLNA
Filamin-A

1

12

High-throughput

0.437

High

1096993

PRDX4
Peroxiredoxin-4

1

6

High-throughput

0.437

High

1291951

NUDC
Nuclear migration protein nudC

1

13

High-throughput

0.437

High

161486

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

Small-scale

0.407

High

396440

ESR1
Estrogen receptor

1

20

Small-scale

0.407

High

1157795

DDB1
DNA damage-binding protein 1

1

11

Small-scale

0.407

High

880454

RPIA
Ribose-5-phosphate isomerase

2

0

High-throughput

0.328

High

1217705

RN220
E3 ubiquitin-protein ligase RNF220

2

0

High-throughput

0.328

High

1291933

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

2

0

High-throughput

0.328

High

1291944

NUDT9
ADP-ribose pyrophosphatase, mitochondrial

2

0

High-throughput

0.328

High

1291947

SELN
Selenoprotein N

2

0

High-throughput

0.328

High

1110270

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

0

High-throughput

0.279

Low

1154492

STXB2
Syntaxin-binding protein 2

1

0

High-throughput

0.279

Low

1178955

TM266
Transmembrane protein 266

1

0

High-throughput

0.279

Low

1206718

RRP12
RRP12-like protein

1

0

High-throughput

0.279

Low

1291932

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.279

Low

1291934

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

1

0

High-throughput

0.279

Low

1291935

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

1010661

DCD
Dermcidin

1

0

High-throughput

0.249

Low

1291936

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025