Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: WNK3 (Q9BYP7)
Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)
Gene: WNK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains OSR1_C~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0072659 - protein localization to plasma membrane
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1311
Hs

1 1800
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Gm
+ At
+ At
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Zm
+ At

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Last updated: 15 Jul 2024