Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5
Interactor 2: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.59 | 0.60 | 0.597 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26700805 |
| Identification Methods | affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006353 - DNA-templated transcription termination GO:0006355 - regulation of DNA-templated transcription |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Sc |   |
|
|||||||||||
| + | Sp | |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
