HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: AP1S2 (P56377)
AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)
Gene: AP1S2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 157
+	Hs
		162577 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1S1_HUMAN (1-157): 6.65e-55: 171: 87.26
+	Hs
		163067 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3S1_HUMAN (1-143): 5.8e-49: 157: 36.91
+	Hs
		162560 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3S2_HUMAN (1-143): 4.58e-47: 153: 36.91
+	Xl
		1140117 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5XGM9_XENLA (1-157): 3.43e-53: 167: 96.88
+	Hs
		163228 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1M1_HUMAN (2-153): 2.63e-43: 149: 19.23
+	Hs
		163116 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2M1_HUMAN (1-153): 7.95e-41: 143: 16.23
+	Xl
		1155750 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q8AVV3_XENLA (1-143): 1.03e-48: 157: 36.24
+	Xl
		1129163 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5M7C4_XENLA (1-143): 2.54e-47: 153: 35.57
+	Hs
		162572 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPZ1_HUMAN (1-154): 4.68e-41: 137: 19.87
+	Xl
		1118800 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q4V857_XENLA (2-153): 2.37e-43: 149: 19.23
+	Xl
		1150206 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6DDI4_XENLA (2-153): 1.13e-41: 145: 18.59
+	Xl
		1155739 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		AP2M1_XENLA (1-153): 4.85e-41: 143: 16.23
+	Sc
		676172 XPO1_YEAST (14-1067): 0: 848: 46.08		AP3S_YEAST (1-156): 2.99e-43: 143: 28.16
+	Sc
		675945 XPO1_YEAST (14-1067): 0: 848: 46.08		AP1S1_YEAST (1-148): 5.7e-43: 141: 53.33
+	Sc
		676282 XPO1_YEAST (14-1067): 0: 848: 46.08		AP2S_YEAST (1-141): 9.78e-43: 140: 41.38
+	Mm
		1322190 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		AP3S1_MOUSE (1-143): 5.8e-49: 157: 36.91