HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~Xpo1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 344
+	Hs
		162664 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		163222 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Hs
		162697 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		162812 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PAP1L_HUMAN (1-195): 2.15e-31: 126: 15.53
+	Xl
		1155766 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		EPABA_XENLA (1-262): 8.29e-30: 121: 13.55
+	Xl
		1155687 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q7ZWX7_XENLA (3-81): 6.02e-28: 109: 45.12
+	Hs
		162702 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		162372 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		162636 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TIAR_HUMAN (102-272): 2.65e-09: 59.9: 13.19
+	Sc
		633922 XPO1_YEAST (14-1067): 0: 848: 46.08		GBP2_YEAST (4-203): 4.8e-23: 100: 19.05
+	Sc
		376677 XPO1_YEAST (14-1067): 0: 848: 46.08		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80
+	Mm
		1112120 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SRSF6_MOUSE (1-322): 3.2e-58: 193: 97.83
+	Mm
		1161051 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SRSF1_MOUSE (3-188): 3.02e-54: 180: 36.65
+	Mm
		1321934 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SRSF9_MOUSE (3-222): 3.56e-49: 166: 35.11
+	Mm
		1257560 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SRSF4_MOUSE (1-316): 2.21e-46: 165: 52.84
+	Mm
		192626 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SRSF5_MOUSE (2-180): 2.78e-46: 160: 64.25
+	At
		186863 MOS14_ARATH (26-1002): 6.38e-104: 350: 13.35		SR34_ARATH (4-289): 3.97e-40: 145: 34.46
+	Mm
		952211 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		SRSF3_MOUSE (3-78): 2.4e-09: 57.4: 46.84
+	At
		1208783 MOS14_ARATH (26-1002): 6.38e-104: 350: 13.35		RSZ33_ARATH (3-89): 5.6e-11: 64.3: 51.14
+	Sc
		965521 MTR10_YEAST (37-715): 9.12e-91: 314: 14.95		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94