HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29346117
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 707
+	Hs
		163237 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TBL1R_HUMAN (251-570): 8.42e-66: 228: 18.58
+	Xl
		1155663 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		TB1RA_XENLA (185-570): 1.42e-65: 227: 16.38
+	Hs
		162856 XPO1_HUMAN (1-1071): 0: 1022: 100.00		FBW10_HUMAN (494-703): 2.61e-34: 142: 26.29
+	Hs
		162576 XPO1_HUMAN (1-1071): 0: 1022: 100.00		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Xl
		1150112 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6DCY8_XENLA (570-706): 5.52e-27: 114: 23.02
+	Hs
		207976 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1060861 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Mm
		903678 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		WDR5_MOUSE (570-706): 2.64e-27: 115: 23.02