HitPredict

Interactor 1: SYN3 (O14994)
Synapsin-3 (Synapsin III)
Gene: SYN3

Interactor 2: SYN2 (Q92777)
Synapsin-2 (Synapsin II)
Gene: SYN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	10358015, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Synapsin~Synapsin_C, Synapsin_C~Synapsin_C
Common GO terms	GO:0005524 - ATP binding GO:0007269 - neurotransmitter secretion GO:0014069 - postsynaptic density GO:0030672 - synaptic vesicle membrane GO:0097091 - synaptic vesicle clustering and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 580 Hs			1 582
+	Hs
		1270571 SYN2_HUMAN (1-580): 0: 709: 53.88		SYN2_HUMAN (1-582): 0: 754: 100.00
+	Hs
		568517 SYN2_HUMAN (1-580): 0: 709: 53.88		SYN1_HUMAN (2-582): 0: 581: 49.58
+	Hs
		568497 SYN1_HUMAN (1-580): 0: 551: 44.19		SYN1_HUMAN (2-582): 0: 581: 49.58
+	Hs
		232742 PHLP1_HUMAN (404-565): 4.78e-21: 100: 19.13		ANR17_HUMAN (406-581): 5.14e-18: 90.6: 16.75
+	Dm
		113976 M9PB30_DROME (377-570): 8.5e-10: 64.4: 12.32		M9PB30_DROME (391-575): 5.43e-09: 61.7: 15.46
+	Mm
		1351630 PCLO_MOUSE (369-573): 2.52e-09: 62.5: 12.96		PCLO_MOUSE (398-578): 4.6e-09: 61.7: 13.74