Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80
Interactor 2: SPC25 (Q9HBM1)
Kinetochore protein Spc25 (hSpc25)
Gene: SPC25
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.756 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 14699129, 33961781, 24981860, 34079125, 20360068, 25416956, unassigned3799 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, mammalian protein protein interaction trap |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000776 - kinetochore GO:0000940 - outer kinetochore GO:0005634 - nucleus GO:0005829 - cytosol GO:0007052 - mitotic spindle organization and 5 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
