HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: CATL1 (P07711)
Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain]
Gene: CTSL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0016324 - apical plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2390 Hs			1 333
+	Hs
		211465 ACTN4_HUMAN (56-621): 3.25e-122: 412: 41.70		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		211501 ACTN4_HUMAN (56-621): 3.25e-122: 412: 41.70		CATS_HUMAN (1-333): 5.17e-142: 406: 47.77
+	Hs
		429812 ACTN1_HUMAN (31-766): 7.87e-88: 310: 32.02		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		429887 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00
+	Hs
		521471 ACTN1_HUMAN (31-766): 7.87e-88: 310: 32.02		CATS_HUMAN (1-333): 5.17e-142: 406: 47.77
+	Hs
		637249 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		CATS_HUMAN (1-333): 5.17e-142: 406: 47.77