HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30309841
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2390 Hs			1 446
+	Hs
		963309 SPTB2_HUMAN (3-2390): 0: 712: 61.09		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		164647 SPTN2_HUMAN (1-2390): 0: 715: 100.00		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		963381 SPTB2_HUMAN (3-2390): 0: 712: 61.09		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		164575 SPTN2_HUMAN (1-2390): 0: 715: 100.00		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		963324 SPTB2_HUMAN (3-2390): 0: 712: 61.09		DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83
+	Hs
		724781 SPTB2_HUMAN (3-2390): 0: 712: 61.09		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1025374 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		211632 ACTN4_HUMAN (56-621): 3.25e-122: 412: 41.70		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		211515 ACTN4_HUMAN (56-621): 3.25e-122: 412: 41.70		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1025396 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		521484 ACTN1_HUMAN (31-766): 7.87e-88: 310: 32.02		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1045471 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		969584 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		CENPE_HUMAN (124-345): 3.98e-10: 64.4: 21.34
+	Hs
		522612 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		MYH7_HUMAN (94-439): 1.46e-09: 62.4: 12.78
+	Hs
		724817 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		944680 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		MAP1A_HUMAN (159-425): 1.97e-12: 71.7: 12.64
+	Hs
		1068617 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		1068548 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		GRDN_HUMAN (135-355): 6.19e-09: 60.6: 21.34
+	Hs
		724839 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		724786 DYST_HUMAN (1807-2150): 4.68e-11: 71: 13.35		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05