HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	N-SET~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1707 Hs			1 328
+	Hs
		165657 SET1A_HUMAN (1-1707): 6.31e-168: 556: 100.00		WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07
+	Hs
		211281 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00
+	Hs
		211190 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00
+	Hs
		211161 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00
+	Hs
		211283 SET1B_HUMAN (257-1707): 2.03e-55: 216: 23.18		BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00
+	Hs
		1080207 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85
+	Hs
		975303 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85
+	Zm
		35725 A0A1D6M742_MAIZE (1110-1704): 9.65e-64: 233: 13.10		A0A1D6LQJ4_MAIZE (1-205): 4.05e-47: 163: 15.14
+	Hs
		1288387 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42
+	Hs
		152559 KMT2D_HUMAN (1567-1707): 6.69e-18: 93.2: 46.15		BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00
+	Hs
		903604 KMT2B_HUMAN (1010-1707): 4.16e-74: 277: 22.55		WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07
+	Hs
		975304 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42
+	Hs
		903149 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07
+	Hs
		331862 NSD2_HUMAN (1405-1706): 1.62e-63: 241: 19.94		SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42
+	Hs
		203735 SUV91_HUMAN (1506-1706): 1.66e-73: 253: 22.75		DAW1_HUMAN (194-319): 2.61e-16: 80.8: 14.17
+	Hs
		267764 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		TAF5L_HUMAN (17-146): 4.7e-09: 59.3: 36.23
+	At
		1319861 ATX1_ARATH (1473-1707): 3.76e-65: 244: 31.41		WDR5A_ARATH (218-319): 1.07e-16: 81.2: 13.08
+	Hs
		1288292 NSD3_HUMAN (1561-1706): 5.1e-55: 213: 30.20		SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42
+	Hs
		903609 SET1B_HUMAN (257-1707): 2.03e-55: 216: 23.18		WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07
+	Dm
		1129076 SET1_DROME (18-215): 6.29e-54: 210: 34.67		WDS_DROME (222-320): 3.76e-18: 85.8: 17.17