Protein: SCAM1
Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1)

Gene: SCAM1, SCAMP1
Organism: Homo sapiens
Interactions: 199
UniProt ID: O15126

Gene Ontology (top 5):
GO:0005802 - trans-Golgi network
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
GO:0006892 - post-Golgi vesicle-mediated transport
GO:0006897 - endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

178694

LYPD3
Ly6/PLAUR domain-containing protein 3

4

1

High-throughput

0.691

High

178769

DLK1
Protein delta homolog 1

4

2

High-throughput

0.691

High

178796

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

4

1

High-throughput

0.691

High

178761

RB11A
Ras-related protein Rab-11A

4

14

High-throughput

0.676

High

163207

TR10B
Tumor necrosis factor receptor superfamily member 10B

3

4

High-throughput

0.667

High

178717

5NTD
5'-nucleotidase

3

1

High-throughput

0.667

High

178718

CD27
CD27 antigen

3

4

High-throughput

0.667

High

178788

MICA
MHC class I polypeptide-related sequence A

3

1

High-throughput

0.667

High

178843

RTN4
Reticulon-4

3

4

High-throughput

0.667

High

178699

RASK
GTPase KRas

3

20

High-throughput

0.640

High

178687

DJC13
DnaJ homolog subfamily C member 13

2

7

High-throughput

0.628

High

178700

TFR1
Transferrin receptor protein 1

2

1

High-throughput

0.611

High

178716

RAB5A
Ras-related protein Rab-5A

2

20

High-throughput

0.611

High

178740

RAB5C
Ras-related protein Rab-5C

2

20

High-throughput

0.611

High

178754

RAB2A
Ras-related protein Rab-2A

2

20

High-throughput

0.611

High

178784

VAMP3
Vesicle-associated membrane protein 3

2

11

High-throughput

0.611

High

178746

ARFP2
Arfaptin-2

2

2

High-throughput

0.606

High

178747

ARFP1
Arfaptin-1

2

2

High-throughput

0.606

High

178776

DCE2
Glutamate decarboxylase 2

2

1

High-throughput

0.606

High

178724

CD70
CD70 antigen

2

0

High-throughput

0.602

High

178708

LAMP2
Lysosome-associated membrane glycoprotein 2

2

8

High-throughput

0.601

High

178839

DNJC5
DnaJ homolog subfamily C member 5

2

5

High-throughput

0.595

High

124147

HAX1
HCLS1-associated protein X-1

2

0

High-throughput

0.585

High

178681

SCAM2
Secretory carrier-associated membrane protein 2

2

5

Small-scale

0.584

High

178682

STX7
Syntaxin-7

2

9

High-throughput

0.584

High

178697

RASN
GTPase NRas

2

20

High-throughput

0.584

High

178706

LAMP1
Lysosome-associated membrane glycoprotein 1

2

8

High-throughput

0.584

High

178715

RAB4A
Ras-related protein Rab-4A

2

20

High-throughput

0.584

High

178742

RAB9A
Ras-related protein Rab-9A

2

20

High-throughput

0.584

High

178760

ARF6
ADP-ribosylation factor 6

2

9

High-throughput

0.584

High

178762

RHOB
Rho-related GTP-binding protein RhoB

2

14

High-throughput

0.584

High

178857

NDRG4
Protein NDRG4

2

0

High-throughput

0.580

High

178772

REEP5
Receptor expression-enhancing protein 5

2

2

High-throughput

0.574

High

178855

S12A6
Solute carrier family 12 member 6

2

6

Small-scale

0.571

High

178738

TTPA
Alpha-tocopherol transfer protein

2

2

High-throughput

0.553

High

178709

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.541

High

164880

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

4

High-throughput

0.536

High

165479

SCAM3
Secretory carrier-associated membrane protein 3

1

5

High-throughput

0.536

High

178696

TSN15
Tetraspanin-15

1

6

High-throughput

0.536

High

178735

NSF
Vesicle-fusing ATPase

1

2

High-throughput

0.536

High

178745

VAMP7
Vesicle-associated membrane protein 7

1

5

High-throughput

0.536

High

178755

RAB5B
Ras-related protein Rab-5B

1

19

High-throughput

0.536

High

178756

RAB14
Ras-related protein Rab-14

1

20

High-throughput

0.536

High

178763

RAB1A
Ras-related protein Rab-1A

1

16

High-throughput

0.536

High

178764

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

High-throughput

0.536

High

178785

RB11B
Ras-related protein Rab-11B

1

19

High-throughput

0.536

High

178789

SHSL1
Protein shisa-like-1

1

1

High-throughput

0.536

High

178803

STX12
Syntaxin-12

1

9

High-throughput

0.536

High

178856

RAB21
Ras-related protein Rab-21

1

20

High-throughput

0.536

High

178861

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

1

1

High-throughput

0.536

High

104860

APRIO
Alternative prion protein

2

3

High-throughput

0.533

High

178783

ITSN1
Intersectin-1

1

1

Small-scale

0.527

High

178814

ZMIZ2
Zinc finger MIZ domain-containing protein 2

1

1

High-throughput

0.523

High

178689

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.515

High

178863

SHLB1
Endophilin-B1

1

1

High-throughput

0.515

High

178688

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

178693

CSPG5
Chondroitin sulfate proteoglycan 5

1

0

High-throughput

0.513

High

178744

CLCN3
H(+)/Cl(-) exchange transporter 3

1

0

High-throughput

0.513

High

178800

T179B
Transmembrane protein 179B

1

0

High-throughput

0.513

High

178833

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

178837

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.513

High

178860

SYNRG
Synergin gamma

1

0

Small-scale

0.504

High

178752

SNP25
Synaptosomal-associated protein 25

1

3

Small-scale

0.501

High

178702

P53
Cellular tumor antigen p53

1

3

High-throughput

0.494

High

178775

UBE3A
Ubiquitin-protein ligase E3A

1

4

High-throughput

0.494

High

178806

WDFY1
WD repeat and FYVE domain-containing protein 1

1

3

High-throughput

0.489

High

178829

BSCL2
Seipin

1

2

High-throughput

0.489

High

178731

EPS15
Epidermal growth factor receptor substrate 15

1

1

Small-scale

0.481

High

123941

SNP23
Synaptosomal-associated protein 23

1

3

Small-scale

0.479

High

126368

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.479

High

178098

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

178680

SCAM1
Secretory carrier-associated membrane protein 1

1

5

Small-scale

0.479

High

178684

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

178685

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

178690

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

178692

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

178695

DIRA3
GTP-binding protein Di-Ras3

1

15

High-throughput

0.479

High

178698

RASH
GTPase HRas

1

20

High-throughput

0.479

High

178704

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

178707

IFM1
Interferon-induced transmembrane protein 1

1

4

High-throughput

0.479

High

178710

RAC2
Ras-related C3 botulinum toxin substrate 2

1

10

High-throughput

0.479

High

178712

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

178713

ARF4
ADP-ribosylation factor 4

1

7

High-throughput

0.479

High

178714

RAB3B
Ras-related protein Rab-3B

1

15

High-throughput

0.479

High

178721

EPHA2
Ephrin type-A receptor 2

1

4

High-throughput

0.479

High

178722

EPHB2
Ephrin type-B receptor 2

1

3

High-throughput

0.479

High

178723

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

178729

ARL1
ADP-ribosylation factor-like protein 1

1

9

High-throughput

0.479

High

178739

EMD
Emerin

1

1

High-throughput

0.479

High

178741

RAB7A
Ras-related protein Rab-7a

1

16

High-throughput

0.479

High

178749

ARL4C
ADP-ribosylation factor-like protein 4C

1

18

High-throughput

0.479

High

178750

RAB25
Ras-related protein Rab-25

1

16

High-throughput

0.479

High

178751

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

178753

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.479

High

178757

ARF3
ADP-ribosylation factor 3

1

7

High-throughput

0.479

High

178758

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

178759

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.479

High

178765

RAC1
Ras-related C3 botulinum toxin substrate 1

1

12

High-throughput

0.479

High

178770

ARF5
ADP-ribosylation factor 5

1

8

High-throughput

0.479

High

178771

RHOG
Rho-related GTP-binding protein RhoG

1

10

High-throughput

0.479

High

178773

IFM3
Interferon-induced transmembrane protein 3

1

4

High-throughput

0.479

High

178777

STX4
Syntaxin-4

1

9

High-throughput

0.479

High

178780

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.479

High

178781

RHOH
Rho-related GTP-binding protein RhoH

1

15

High-throughput

0.479

High

178786

NTRK3
NT-3 growth factor receptor

1

3

High-throughput

0.479

High

178792

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

178794

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

178795

STYK1
Tyrosine-protein kinase STYK1

1

3

High-throughput

0.479

High

178799

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

178801

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

1

High-throughput

0.479

High

178808

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

178809

ARL14
ADP-ribosylation factor-like protein 14

1

10

High-throughput

0.479

High

178811

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

178817

RFFL
E3 ubiquitin-protein ligase rififylin

1

2

Small-scale

0.479

High

178821

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.479

High

178822

ARL11
ADP-ribosylation factor-like protein 11

1

16

High-throughput

0.479

High

178827

ARL8A
ADP-ribosylation factor-like protein 8A

1

10

High-throughput

0.479

High

178830

ARL5B
ADP-ribosylation factor-like protein 5B

1

11

High-throughput

0.479

High

178832

SL9A7
Sodium/hydrogen exchanger 7

1

2

Small-scale

0.479

High

178834

VAMP8
Vesicle-associated membrane protein 8

1

10

High-throughput

0.479

High

178840

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.479

High

178845

ARL8B
ADP-ribosylation factor-like protein 8B

1

16

High-throughput

0.479

High

178847

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

178851

ANFY1
Rabankyrin-5

1

1

High-throughput

0.479

High

178853

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

178854

DNJ5B
DnaJ homolog subfamily C member 5B

1

5

High-throughput

0.479

High

178859

ALK
ALK tyrosine kinase receptor

1

4

High-throughput

0.479

High

178862

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.479

High

178864

ARL5A
ADP-ribosylation factor-like protein 5A

1

12

High-throughput

0.479

High

155979

SOCS6
Suppressor of cytokine signaling 6

1

3

High-throughput

0.470

High

178826

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

178727

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

171630

GAK
Cyclin-G-associated kinase

1

0

High-throughput

0.458

High

178683

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.458

High

178703

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

178733

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

178736

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

178766

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.458

High

178767

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

178774

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

178779

PLSI
Plastin-1

1

0

High-throughput

0.458

High

178787

OCLN
Occludin

1

0

High-throughput

0.458

High

178819

GOGA1
Golgin subfamily A member 1

1

0

High-throughput

0.458

High

178823

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

178831

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

178835

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

178842

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

178850

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

178686

S19A2
Thiamine transporter 1

1

4

High-throughput

0.445

High

178705

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

178812

VGLU3
Vesicular glutamate transporter 3

1

4

High-throughput

0.445

High

178815

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

178818

LPAR1
Lysophosphatidic acid receptor 1

1

9

High-throughput

0.445

High

178820

RAB1C
Putative Ras-related protein Rab-1C

1

13

High-throughput

0.445

High

178852

VGLU2
Vesicular glutamate transporter 2

1

4

High-throughput

0.445

High

178728

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

139767

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

178711

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

178719

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

178725

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

178730

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

178768

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

178778

MAP7
Ensconsin

1

2

High-throughput

0.437

High

178782

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.437

High

178790

MIDN
Midnolin

1

2

High-throughput

0.437

High

178797

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

178802

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

178810

DHB11
Estradiol 17-beta-dehydrogenase 11

1

4

High-throughput

0.437

High

178836

RAB1B
Ras-related protein Rab-1B

1

13

High-throughput

0.437

High

178844

SAR1A
Small COPII coat GTPase SAR1A

1

14

High-throughput

0.437

High

178846

ARL15
ADP-ribosylation factor-like protein 15

1

16

High-throughput

0.437

High

178865

SAR1B
Small COPII coat GTPase SAR1B

1

13

High-throughput

0.437

High

161113

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.426

High

178701

PRIO
Major prion protein

1

0

High-throughput

0.426

High

178732

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

178841

VIAAT
Vesicular inhibitory amino acid transporter

1

0

High-throughput

0.426

High

178805

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

178813

ZNT7
Zinc transporter 7

1

2

High-throughput

0.407

High

178734

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

0

High-throughput

0.316

High

178737

PCY1A
Choline-phosphate cytidylyltransferase A

2

0

High-throughput

0.316

High

178816

THAP4
Peroxynitrite isomerase THAP4

2

0

High-throughput

0.316

High

178824

FAKD4
FAST kinase domain-containing protein 4

2

0

High-throughput

0.316

High

178828

MTEF3
Transcription termination factor 3, mitochondrial

2

0

High-throughput

0.316

High

178849

SPG21
Maspardin

2

0

High-throughput

0.316

High

178791

TASO2
Protein TASOR 2

1

0

High-throughput

0.299

High

178720

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.279

Low

178726

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.279

Low

178793

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

0

High-throughput

0.279

Low

178748

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

178804

KR131
Keratin-associated protein 13-1

1

0

High-throughput

0.251

Low

178691

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.249

Low

178743

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.249

Low

178798

MOB2
MOB kinase activator 2

1

0

High-throughput

0.249

Low

178807

DEN6A
Protein DENND6A

1

0

High-throughput

0.249

Low

178825

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

178838

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

178848

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.249

Low

178858

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025