HitPredict

Interactor 1: SYNEM (O15061)
Synemin (Desmuslin)
Gene: SYNM

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	29924966
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1565 Hs			1 1480
+	Hs
		359298 K1C14_HUMAN (9-349): 1.21e-141: 446: 23.98		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529011 K1C17_HUMAN (6-328): 7.11e-138: 434: 26.54		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		444998 K1C16_HUMAN (7-336): 6.38e-136: 430: 25.68		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528449 K1C13_HUMAN (6-335): 3.69e-135: 427: 22.89		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		444303 K1C19_HUMAN (6-330): 8.56e-134: 421: 23.01		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529118 KT33B_HUMAN (9-319): 1.97e-133: 421: 26.60		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		280490 KT33A_HUMAN (9-332): 4.58e-101: 332: 25.23		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529130 K2C72_HUMAN (3-325): 6.34e-63: 226: 18.77		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528760 K2C6C_HUMAN (4-325): 4.14e-61: 222: 19.44		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		380440 K2C6B_HUMAN (4-325): 6.21e-61: 221: 19.44		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528450 K2C5_HUMAN (4-325): 2.24e-60: 220: 18.83		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		359458 K2C6A_HUMAN (4-325): 1.18e-59: 218: 19.44		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		443292 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528496 DESM_HUMAN (11-320): 1.59e-20: 99: 31.29		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529119 KRT81_HUMAN (142-456): 5.36e-12: 72.1: 9.73		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		213928 KRT86_HUMAN (142-456): 8.98e-12: 71.4: 9.73		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529503 KRT35_HUMAN (101-386): 4.12e-11: 69.1: 11.18		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528963 KRT85_HUMAN (152-456): 1.99e-10: 67.1: 9.97		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		443691 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		ABCAA_HUMAN (46-1480): 1.11e-146: 489: 12.74
+	Hs
		422441 NFM_HUMAN (4-318): 3.87e-17: 89.7: 27.36		MRP9_HUMAN (129-648): 1.25e-56: 218: 14.61