Protein: ZN646
Zinc finger protein 646

Gene: ZN646, ZNF646
Organism: Homo sapiens
Interactions: 40
UniProt ID: O15015

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

174439

KGP1
cGMP-dependent protein kinase 1

2

1

High-throughput

0.725

High

174446

ZN668
Zinc finger protein 668

1

8

High-throughput

0.691

High

174452

ZBT47
Zinc finger and BTB domain-containing protein 47

1

17

High-throughput

0.691

High

174449

MDFI
MyoD family inhibitor

2

1

High-throughput

0.640

High

174427

RGS3
Regulator of G-protein signaling 3

2

2

High-throughput

0.628

High

174433

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

16

High-throughput

0.628

High

71825

LEUTX
Paired-like homeodomain transcription factor LEUTX

2

1

High-throughput

0.606

High

174444

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

2

High-throughput

0.573

High

174428

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.541

High

174434

TRAF2
TNF receptor-associated factor 2

1

10

High-throughput

0.541

High

174420

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

16

High-throughput

0.536

High

174424

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.536

High

174431

NOTC2
Neurogenic locus notch homolog protein 2

1

7

High-throughput

0.536

High

174432

SRSF4
Serine/arginine-rich splicing factor 4

1

12

High-throughput

0.536

High

174443

H1FNT
Testis-specific H1 histone

1

2

High-throughput

0.536

High

174445

DGCR8
Microprocessor complex subunit DGCR8

1

2

High-throughput

0.536

High

174451

REXO4
RNA exonuclease 4

1

3

High-throughput

0.536

High

174422

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.515

High

174454

NINL
Ninein-like protein

1

5

High-throughput

0.494

High

166098

AIM2
Interferon-inducible protein AIM2

1

1

High-throughput

0.489

High

174425

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.489

High

174426

RS10
Small ribosomal subunit protein eS10

1

4

High-throughput

0.489

High

174430

RL19
Large ribosomal subunit protein eL19

1

4

High-throughput

0.489

High

174436

SRSF5
Serine/arginine-rich splicing factor 5

1

12

High-throughput

0.489

High

174437

KRR1
KRR1 small subunit processome component homolog

1

4

High-throughput

0.489

High

174440

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

15

High-throughput

0.489

High

174441

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.489

High

174442

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.489

High

174455

RL36
Large ribosomal subunit protein eL36

1

8

High-throughput

0.489

High

174423

H2AB2
Histone H2A-Bbd type 2/3

1

2

High-throughput

0.479

High

174429

RNF4
E3 ubiquitin-protein ligase RNF4

1

16

High-throughput

0.479

High

174435

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

174438

CUL3
Cullin-3

1

20

High-throughput

0.479

High

174448

CIC
Protein capicua homolog

1

3

High-throughput

0.479

High

174450

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

174453

BRPF3
Bromodomain and PHD finger-containing protein 3

1

2

High-throughput

0.479

High

174447

CI072
Guanine nucleotide exchange factor C9orf72

1

2

Small-scale

0.445

High

104852

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

165786

TR13B
Tumor necrosis factor receptor superfamily member 13B

2

0

High-throughput

0.328

High

174421

NSA2
Ribosome biogenesis protein NSA2 homolog

2

0

High-throughput

0.318

High


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Last updated: 11Aug2025