HitPredict

Interactor 1: SYNEM (O15061)
Synemin (Desmuslin)
Gene: SYNM

Interactor 2: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	26638075, 34079125, 35709258
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1565 Hs			1 1140
+	Hs
		725143 K1C17_HUMAN (6-328): 7.11e-138: 434: 26.54		MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95
+	Hs
		49550 A1A4E9_HUMAN (6-335): 5.18e-135: 427: 22.89		MYH1_HUMAN (474-1139): 2.79e-35: 148: 12.92
+	Hs
		522534 K1C13_HUMAN (6-335): 3.69e-135: 427: 22.89		MYH1_HUMAN (474-1139): 2.79e-35: 148: 12.92
+	Hs
		724787 K1C17_HUMAN (6-328): 7.11e-138: 434: 26.54		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93
+	Hs
		551676 K1C17_HUMAN (6-328): 7.11e-138: 434: 26.54		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		444307 K1C19_HUMAN (6-330): 8.56e-134: 421: 23.01		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		1081722 AINX_HUMAN (11-318): 1.33e-23: 108: 32.58		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		821776 NEST_HUMAN (9-320): 3.62e-19: 96.7: 33.33		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		531529 K2C5_HUMAN (4-325): 2.24e-60: 220: 18.83		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		359462 K2C6A_HUMAN (4-325): 1.18e-59: 218: 19.44		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		359533 K2C6A_HUMAN (4-325): 1.18e-59: 218: 19.44		TSG10_HUMAN (187-806): 2.38e-12: 73.2: 14.19
+	Hs
		821772 NEST_HUMAN (9-320): 3.62e-19: 96.7: 33.33		GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61
+	Mm
		93542 NFL_MOUSE (11-318): 3.96e-23: 107: 28.90		DESP_MOUSE (212-1059): 2.19e-26: 120: 14.43
+	Hs
		443305 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Mm
		589637 VIME_MOUSE (11-320): 4.11e-31: 130: 33.12		TSG10_MOUSE (187-806): 6.26e-13: 75.1: 14.36
+	Hs
		443784 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		TSG10_HUMAN (187-806): 2.38e-12: 73.2: 14.19
+	Hs
		535318 GFAP_HUMAN (11-320): 4.41e-27: 118: 32.58		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		551630 PERI_HUMAN (11-320): 1.18e-22: 105: 31.83		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		551603 DESM_HUMAN (11-320): 1.59e-20: 99: 31.29		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86
+	Hs
		422342 NFM_HUMAN (4-318): 3.87e-17: 89.7: 27.36		DESP_HUMAN (400-1134): 5.73e-13: 75.9: 11.86