Protein: NEDD4
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)

Gene: NEDD4
Organism: Homo sapiens
Interactions: 475
UniProt ID: P46934

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000151 - ubiquitin ligase complex
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

808040

NEDD4
E3 ubiquitin-protein ligase NEDD4

25

18

Small-scale

0.991

High

808069

UB2D3
Ubiquitin-conjugating enzyme E2 D3

17

20

Small-scale

0.986

High

808084

UB2L3
Ubiquitin-conjugating enzyme E2 L3

18

20

Small-scale

0.986

High

808078

UB2D2
Ubiquitin-conjugating enzyme E2 D2

18

20

Small-scale

0.986

High

808052

UB2D1
Ubiquitin-conjugating enzyme E2 D1

12

20

Small-scale

0.978

High

808057

UB2E1
Ubiquitin-conjugating enzyme E2 E1

7

20

Small-scale

0.967

High

475470

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

7

20

Small-scale

0.965

High

808276

SMUF2
E3 ubiquitin-protein ligase SMURF2

4

18

Small-scale

0.899

High

474953

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

20

Small-scale

0.799

High

808067

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

16

12

Small-scale

0.763

High

808049

SCNNB
Amiloride-sensitive sodium channel subunit beta

9

20

Small-scale

0.755

High

397834

ISG15
Ubiquitin-like protein ISG15

2

20

Small-scale

0.754

High

808041

YAP1
Transcriptional coactivator YAP1

2

19

Small-scale

0.754

High

739582

SCNNA
Amiloride-sensitive sodium channel subunit alpha

7

20

Small-scale

0.752

High

808216

ARRD3
Arrestin domain-containing protein 3

7

20

Small-scale

0.751

High

808210

WBP2
WW domain-binding protein 2

7

7

Small-scale

0.751

High

808211

PMEPA
Protein TMEPAI

7

12

Small-scale

0.750

High

808291

NFIP2
NEDD4 family-interacting protein 2

7

17

Small-scale

0.749

High

808273

SAV1
Protein salvador homolog 1

1

18

Small-scale

0.747

High

808261

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

6

9

Small-scale

0.740

High

808087

SMAD3
Mothers against decapentaplegic homolog 3

6

20

Small-scale

0.734

High

808333

RNF11
RING finger protein 11

6

14

Small-scale

0.733

High

808241

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

5

8

Small-scale

0.726

High

384459

NTRK1
High affinity nerve growth factor receptor

5

14

Small-scale

0.724

High

808257

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

5

14

Small-scale

0.720

High

808187

ARRD1
Arrestin domain-containing protein 1

5

20

Small-scale

0.719

High

808050

SCNNG
Amiloride-sensitive sodium channel subunit gamma

5

20

Small-scale

0.718

High

808068

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

4

9

Small-scale

0.710

High

808265

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

4

9

Small-scale

0.710

High

808136

EREP1
Endosomal transmembrane epsin interactor 1

4

14

High-throughput

0.696

High

808116

LAPM5
Lysosomal-associated transmembrane protein 5

4

7

Small-scale

0.694

High

808235

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

18

High-throughput

0.691

High

808278

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

18

High-throughput

0.691

High

808062

PSMD4
26S proteasome non-ATPase regulatory subunit 4

4

6

Small-scale

0.688

High

116984

SGK1
Serine/threonine-protein kinase Sgk1

4

20

Small-scale

0.686

High

507904

FGFR1
Fibroblast growth factor receptor 1

3

17

Small-scale

0.684

High

808115

SQSTM
Sequestosome-1

4

5

Small-scale

0.683

High

681731

AKT1
RAC-alpha serine/threonine-protein kinase

3

20

Small-scale

0.680

High

808127

BECN1
Beclin-1

3

1

Small-scale

0.674

High

566962

CXA1
Gap junction alpha-1 protein

4

2

Small-scale

0.671

High

808146

MAR1
Melanoma antigen recognized by T-cells 1

3

1

Small-scale

0.671

High

159925

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

3

16

Small-scale

0.667

High

624804

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

10

Small-scale

0.667

High

740458

PPARG
Peroxisome proliferator-activated receptor gamma

3

11

Small-scale

0.667

High

742119

SYUA
Alpha-synuclein

3

4

Small-scale

0.667

High

808335

RPGF2
Rap guanine nucleotide exchange factor 2

3

4

Small-scale

0.667

High

808149

TM52B
Transmembrane protein 52B

3

1

High-throughput

0.667

High

808226

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

18

Small-scale

0.665

High

338105

EGFR
Epidermal growth factor receptor

3

20

Small-scale

0.662

High

175841

P73
Tumor protein p73

3

15

Small-scale

0.660

High

808249

NFIP1
NEDD4 family-interacting protein 1

3

17

Small-scale

0.660

High

306025

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

9

Small-scale

0.655

High

808070

UBC12
NEDD8-conjugating enzyme Ubc12

1

20

High-throughput

0.647

High

808282

BIRC6
Baculoviral IAP repeat-containing protein 6

1

20

Small-scale

0.647

High

435577

IGF1R
Insulin-like growth factor 1 receptor

3

13

Small-scale

0.646

High

528744

CFTR
Cystic fibrosis transmembrane conductance regulator

3

4

Small-scale

0.643

High

808130

LAP4A
Lysosomal-associated transmembrane protein 4A

3

11

Small-scale

0.640

High

808151

AMOT
Angiomotin

2

20

Small-scale

0.639

High

170532

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

4

12

High-throughput

0.636

High

808292

TMM51
Transmembrane protein 51

4

5

High-throughput

0.636

High

808104

ACK1
Activated CDC42 kinase 1

2

20

Small-scale

0.634

High

808132

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

20

Small-scale

0.634

High

486014

RAP2A
Ras-related protein Rap-2a

2

3

Small-scale

0.629

High

808160

OTU1
Ubiquitin thioesterase OTU1

2

1

Small-scale

0.629

High

808239

M3K5
Mitogen-activated protein kinase kinase kinase 5

2

20

Small-scale

0.629

High

808254

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

9

Small-scale

0.629

High

808306

RBX2
RING-box protein 2

2

5

Small-scale

0.629

High

808315

TNIK
TRAF2 and NCK-interacting protein kinase

2

20

Small-scale

0.629

High

808142

OCLN
Occludin

2

5

High-throughput

0.628

High

808174

ILDR1
Immunoglobulin-like domain-containing receptor 1

2

5

High-throughput

0.628

High

808205

SUSD6
Sushi domain-containing protein 6

2

1

High-throughput

0.628

High

808287

TNR19
Tumor necrosis factor receptor superfamily member 19

2

3

High-throughput

0.628

High

156470

SCAM3
Secretory carrier-associated membrane protein 3

2

3

Small-scale

0.625

High

808217

TMIG2
Transmembrane and immunoglobulin domain-containing protein 2

1

0

Small-scale

0.625

High

325655

LATS1
Serine/threonine-protein kinase LATS1

2

15

Small-scale

0.624

High

601847

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

Small-scale

0.624

High

808047

NUMB
Protein numb homolog

2

2

Small-scale

0.624

High

808128

SCN5A
Sodium channel protein type 5 subunit alpha

2

20

Small-scale

0.619

High

808330

M3K2
Mitogen-activated protein kinase kinase kinase 2

2

10

High-throughput

0.619

High

152184

TMG1
Transmembrane gamma-carboxyglutamic acid protein 1

2

14

High-throughput

0.619

High

808092

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

2

5

High-throughput

0.619

High

808183

AMOL1
Angiomotin-like protein 1

2

20

High-throughput

0.619

High

808186

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

2

4

High-throughput

0.619

High

808232

M4A10
Membrane-spanning 4-domains subfamily A member 10

2

2

High-throughput

0.619

High

808272

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

2

9

Small-scale

0.619

High

226796

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.618

High

808083

UBC9
SUMO-conjugating enzyme UBC9

1

20

Small-scale

0.618

High

808299

PD1L1
Programmed cell death 1 ligand 1

1

6

Small-scale

0.618

High

297702

DEND
Dendrin

1

0

High-throughput

0.614

High

808094

MDM2
E3 ubiquitin-protein ligase Mdm2

2

4

Small-scale

0.613

High

546967

EZRI
Ezrin

2

8

Small-scale

0.611

High

808077

1433E
14-3-3 protein epsilon

2

12

High-throughput

0.611

High

808086

EREP3
Protein ENTREP3

3

14

High-throughput

0.609

High

808155

T255A
Transmembrane protein 255A

3

5

High-throughput

0.609

High

808166

TMM92
Transmembrane protein 92

3

2

High-throughput

0.609

High

808204

TM171
Transmembrane protein 171

3

4

High-throughput

0.609

High

808224

WBP1
WW domain-binding protein 1

3

10

High-throughput

0.609

High

169809

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

8

High-throughput

0.606

High

808059

PLK1
Serine/threonine-protein kinase PLK1

2

6

Small-scale

0.602

High

808234

TREF1
Transcriptional-regulating factor 1

2

5

High-throughput

0.602

High

808274

RPAP3
RNA polymerase II-associated protein 3

2

14

High-throughput

0.602

High

808305

UVRAG
UV radiation resistance-associated gene protein

2

2

High-throughput

0.602

High

685841

ARRB2
Beta-arrestin-2

2

4

Small-scale

0.601

High

808135

SMAD1
Mothers against decapentaplegic homolog 1

2

20

Small-scale

0.600

High

808100

SC6A3
Sodium-dependent dopamine transporter

2

1

Small-scale

0.595

High

808260

TTYH3
Protein tweety homolog 3

2

2

Small-scale

0.595

High

808309

TBK1
Serine/threonine-protein kinase TBK1

2

13

Small-scale

0.595

High

808196

PRR7
Proline-rich protein 7

2

0

High-throughput

0.592

High

167342

SMAD7
Mothers against decapentaplegic homolog 7

2

20

Small-scale

0.584

High

262241

ULK1
Serine/threonine-protein kinase ULK1

2

16

Small-scale

0.584

High

428963

ADRB2
Beta-2 adrenergic receptor

2

3

Small-scale

0.584

High

786690

GRIA1
Glutamate receptor 1

2

1

Small-scale

0.584

High

799896

ABCG1
ATP-binding cassette sub-family G member 1

2

2

Small-scale

0.584

High

808176

LAP4B
Lysosomal-associated transmembrane protein 4B

2

11

Small-scale

0.584

High

808286

LATS2
Serine/threonine-protein kinase LATS2

2

20

Small-scale

0.584

High

522850

SRC
Proto-oncogene tyrosine-protein kinase Src

1

14

Small-scale

0.578

High

620132

PAX7
Paired box protein Pax-7

1

1

Small-scale

0.578

High

799938

VDAC2
Voltage-dependent anion-selective channel protein 2

1

5

Small-scale

0.578

High

808248

TTYH2
Protein tweety homolog 2

1

2

Small-scale

0.578

High

808314

ERRFI
ERBB receptor feedback inhibitor 1

1

9

Small-scale

0.578

High

808326

VDAC3
Voltage-dependent anion-selective channel protein 3

1

5

Small-scale

0.578

High

808336

IRS2
Insulin receptor substrate 2

1

7

Small-scale

0.578

High

808258

TMG3
Transmembrane gamma-carboxyglutamic acid protein 3

2

14

High-throughput

0.574

High

808219

ESS2
Splicing factor ESS-2 homolog

2

1

High-throughput

0.571

High

808250

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

2

15

High-throughput

0.571

High

808244

TS101
Tumor susceptibility gene 101 protein

2

1

Small-scale

0.571

High

808312

SRTD1
SERTA domain-containing protein 1

2

0

Small-scale

0.569

High

208105

SPY2
Protein sprouty homolog 2

1

3

Small-scale

0.561

High

231384

PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

1

5

Small-scale

0.561

High

379117

MYCN
N-myc proto-oncogene protein

1

8

Small-scale

0.561

High

434157

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

Small-scale

0.561

High

632639

TYY1
Transcriptional repressor protein YY1

1

4

High-throughput

0.561

High

646524

ANX13
Annexin A13

1

7

Small-scale

0.561

High

729209

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

5

Small-scale

0.561

High

808056

CCNH
Cyclin-H

1

3

Small-scale

0.561

High

808063

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

Small-scale

0.561

High

808080

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.561

High

808088

H33
Histone H3.3

1

4

Small-scale

0.561

High

808099

IFM3
Interferon-induced transmembrane protein 3

1

3

Small-scale

0.561

High

808106

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.561

High

808111

CBLB
E3 ubiquitin-protein ligase CBL-B

1

9

Small-scale

0.561

High

808242

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

5

Small-scale

0.561

High

808267

TRPV6
Transient receptor potential cation channel subfamily V member 6

1

3

Small-scale

0.561

High

808296

MTMR4
Myotubularin-related protein 4

1

3

Small-scale

0.561

High

808206

RTF1
RNA polymerase-associated protein RTF1 homolog

1

0

High-throughput

0.554

High

808118

ASPP2
Apoptosis-stimulating of p53 protein 2

2

12

Small-scale

0.554

High

401608

JUN
Transcription factor Jun

1

6

Small-scale

0.552

High

808245

SMO
Protein smoothened

1

1

Small-scale

0.552

High

276359

AP1G2
AP-1 complex subunit gamma-like 2

1

0

Small-scale

0.537

High

352992

IL1B
Interleukin-1 beta

1

0

Small-scale

0.537

High

808222

THOC1
THO complex subunit 1

1

0

Small-scale

0.537

High

808280

KCJ16
Inward rectifier potassium channel 16

1

0

Small-scale

0.537

High

808334

KAD6
Adenylate kinase isoenzyme 6

1

0

Small-scale

0.537

High

337392

ABL1
Tyrosine-protein kinase ABL1

1

12

High-throughput

0.536

High

412081

FYN
Tyrosine-protein kinase Fyn

1

14

High-throughput

0.536

High

452372

PGFRB
Platelet-derived growth factor receptor beta

1

13

High-throughput

0.536

High

572597

VGFR1
Vascular endothelial growth factor receptor 1

1

11

High-throughput

0.536

High

601478

FGFR2
Fibroblast growth factor receptor 2

1

16

High-throughput

0.536

High

808090

CDK5
Cyclin-dependent kinase 5

1

5

High-throughput

0.536

High

808167

RBP10
Ran-binding protein 10

1

14

High-throughput

0.536

High

808179

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

1

5

High-throughput

0.536

High

808198

DDX54
ATP-dependent RNA helicase DDX54

1

20

High-throughput

0.536

High

808212

TRI52
E3 ubiquitin-protein ligase TRIM52

1

4

High-throughput

0.536

High

808243

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

12

High-throughput

0.536

High

808293

CUED1
CUE domain-containing protein 1

1

6

High-throughput

0.536

High

808324

AKT3
RAC-gamma serine/threonine-protein kinase

1

19

High-throughput

0.536

High

253886

LRP3
Low-density lipoprotein receptor-related protein 3

1

18

High-throughput

0.536

High

265967

PSIP1
PC4 and SFRS1-interacting protein

1

3

High-throughput

0.536

High

336407

SODC
Superoxide dismutase [Cu-Zn]

1

4

High-throughput

0.536

High

340408

PGK1
Phosphoglycerate kinase 1

1

2

High-throughput

0.536

High

415248

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.536

High

417186

ENOA
Alpha-enolase

1

7

High-throughput

0.536

High

418907

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.536

High

427484

ANXA2
Annexin A2

1

8

High-throughput

0.536

High

444859

ANXA5
Annexin A5

1

7

High-throughput

0.536

High

447661

ENOG
Gamma-enolase

1

7

High-throughput

0.536

High

453208

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

17

High-throughput

0.536

High

519149

KCRB
Creatine kinase B-type

1

2

High-throughput

0.536

High

535814

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.536

High

538146

ENPL
Endoplasmin

1

12

High-throughput

0.536

High

562900

STMN1
Stathmin

1

1

High-throughput

0.536

High

578291

PGAM1
Phosphoglycerate mutase 1

1

5

High-throughput

0.536

High

609749

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

15

High-throughput

0.536

High

614270

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

7

High-throughput

0.536

High

643263

HMGB2
High mobility group protein B2

1

12

High-throughput

0.536

High

653510

CALR
Calreticulin

1

4

High-throughput

0.536

High

666858

TKT
Transketolase

1

4

High-throughput

0.536

High

669918

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.536

High

670909

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

7

High-throughput

0.536

High

671744

PDIA3
Protein disulfide-isomerase A3

1

8

High-throughput

0.536

High

678421

S10A7
Protein S100-A7

1

4

High-throughput

0.536

High

683192

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

685634

PRDX2
Peroxiredoxin-2

1

7

High-throughput

0.536

High

763316

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

4

High-throughput

0.536

High

777492

MDHM
Malate dehydrogenase, mitochondrial

1

5

High-throughput

0.536

High

808064

IF6
Eukaryotic translation initiation factor 6

1

2

High-throughput

0.536

High

808066

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.536

High

808073

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.536

High

808074

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.536

High

808076

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

808081

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

808085

BASP1
Brain acid soluble protein 1

1

2

High-throughput

0.536

High

808095

SET
Protein SET

1

5

High-throughput

0.536

High

808102

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

808105

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.536

High

808121

NACA
Nascent polypeptide-associated complex subunit alpha

1

4

High-throughput

0.536

High

808122

DX39B
Spliceosome RNA helicase DDX39B

1

13

High-throughput

0.536

High

808175

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

4

High-throughput

0.536

High

808185

PALS1
Protein PALS1

1

8

High-throughput

0.536

High

808207

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

4

High-throughput

0.536

High

808237

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.536

High

808252

LFG2
Protein lifeguard 2

1

1

High-throughput

0.536

High

808279

S10AE
Protein S100-A14

1

4

High-throughput

0.536

High

808281

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

4

High-throughput

0.536

High

808323

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

3

High-throughput

0.536

High

808328

AMOL2
Angiomotin-like protein 2

1

17

High-throughput

0.536

High

808338

RBM8A
RNA-binding protein 8A

1

6

High-throughput

0.536

High

159031

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

20

High-throughput

0.527

High

426596

H10
Histone H1.0

1

2

High-throughput

0.515

High

586013

SL9A1
Sodium/hydrogen exchanger 1

1

1

Small-scale

0.515

High

808058

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

6

High-throughput

0.515

High

808271

FXL15
F-box/LRR-repeat protein 15

1

10

Small-scale

0.515

High

808103

Q05BL1
TP53BP2 protein

1

9

High-throughput

0.515

High

808228

MY15B
Unconventional myosin-XVB

1

4

High-throughput

0.515

High

301041

RNF37
RING finger protein 37

1

0

High-throughput

0.513

High

170046

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.513

High

352921

IFNG
Interferon gamma

1

0

High-throughput

0.513

High

396899

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.513

High

414592

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.513

High

430090

PROF1
Profilin-1

1

0

High-throughput

0.513

High

564829

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

596468

PTMS
Parathymosin

1

0

High-throughput

0.513

High

671618

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.513

High

808098

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.513

High

808123

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

808214

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.513

High

808313

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.513

High

514354

PSPC
Surfactant protein C

1

3

Small-scale

0.512

High

808240

SMAD5
Mothers against decapentaplegic homolog 5

1

20

High-throughput

0.508

High

673553

MPIP3
M-phase inducer phosphatase 3

1

0

Small-scale

0.505

High

48998

SHOT1
Shootin-1

1

1

High-throughput

0.501

High

131554

STK25
Serine/threonine-protein kinase 25

1

20

High-throughput

0.501

High

133919

DDX3X
ATP-dependent RNA helicase DDX3X

1

11

High-throughput

0.501

High

146175

ARI1A
AT-rich interactive domain-containing protein 1A

1

13

High-throughput

0.501

High

150684

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

Small-scale

0.501

High

156002

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

9

High-throughput

0.501

High

173361

CLIC2
Chloride intracellular channel protein 2

1

2

High-throughput

0.501

High

175425

SIVA
Apoptosis regulatory protein Siva

1

1

High-throughput

0.501

High

200165

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

9

High-throughput

0.501

High

214877

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

4

High-throughput

0.501

High

237568

DIAP1
Protein diaphanous homolog 1

1

1

High-throughput

0.501

High

241153

TOM1
Target of Myb1 membrane trafficking protein

1

14

High-throughput

0.501

High

272855

KS6A4
Ribosomal protein S6 kinase alpha-4

1

10

High-throughput

0.501

High

295605

RMP
Unconventional prefoldin RPB5 interactor 1

1

3

High-throughput

0.501

High

373858

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

16

High-throughput

0.501

High

375718

GBA1
Lysosomal acid glucosylceramidase

1

1

High-throughput

0.501

High

426951

FES
Tyrosine-protein kinase Fes/Fps

1

17

High-throughput

0.501

High

430890

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

9

High-throughput

0.501

High

433282

YES
Tyrosine-protein kinase Yes

1

14

High-throughput

0.501

High

540926

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

8

High-throughput

0.501

High

575323

EGR1
Early growth response protein 1

1

3

High-throughput

0.501

High

583423

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

8

High-throughput

0.501

High

583667

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

3

High-throughput

0.501

High

616684

KS6B1
Ribosomal protein S6 kinase beta-1

1

20

High-throughput

0.501

High

653190

PYR1
Multifunctional protein CAD

1

11

High-throughput

0.501

High

673254

WEE1
Wee1-like protein kinase

1

15

High-throughput

0.501

High

676831

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

8

High-throughput

0.501

High

687021

GRK4
G protein-coupled receptor kinase 4

1

13

High-throughput

0.501

High

723839

SCN1A
Sodium channel protein type 1 subunit alpha

1

20

High-throughput

0.501

High

724520

IRS1
Insulin receptor substrate 1

1

7

High-throughput

0.501

High

729242

VGFR3
Vascular endothelial growth factor receptor 3

1

13

High-throughput

0.501

High

738312

BMR1A
Bone morphogenetic protein receptor type-1A

1

19

High-throughput

0.501

High

787863

EPS15
Epidermal growth factor receptor substrate 15

1

3

Small-scale

0.501

High

789045

ABL2
Tyrosine-protein kinase ABL2

1

12

High-throughput

0.501

High

796526

KSYK
Tyrosine-protein kinase SYK

1

20

High-throughput

0.501

High

808045

RM19
Large ribosomal subunit protein bL19m

1

2

High-throughput

0.501

High

808048

CLK3
Dual specificity protein kinase CLK3

1

9

High-throughput

0.501

High

808054

KS6A3
Ribosomal protein S6 kinase alpha-3

1

14

High-throughput

0.501

High

808055

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

15

High-throughput

0.501

High

808060

EPHA5
Ephrin type-A receptor 5

1

9

High-throughput

0.501

High

808071

RS3A
Small ribosomal subunit protein eS1

1

7

High-throughput

0.501

High

808072

FGF12
Fibroblast growth factor 12

1

4

High-throughput

0.501

High

808075

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

16

High-throughput

0.501

High

808093

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

15

High-throughput

0.501

High

808096

RUNX1
Runt-related transcription factor 1

1

11

Small-scale

0.501

High

808097

AMPD2
AMP deaminase 2

1

1

High-throughput

0.501

High

808107

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

5

High-throughput

0.501

High

808108

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

4

Small-scale

0.501

High

808109

ANK3
Ankyrin-3

1

6

High-throughput

0.501

High

808110

STK4
Serine/threonine-protein kinase 4

1

20

High-throughput

0.501

High

808112

KGP2
cGMP-dependent protein kinase 2

1

17

High-throughput

0.501

High

808113

KCAB2
Voltage-gated potassium channel subunit beta-2

1

4

High-throughput

0.501

High

808124

KLF5
Krueppel-like factor 5

1

10

High-throughput

0.501

High

808125

UBP2L
Ubiquitin-associated protein 2-like

1

10

High-throughput

0.501

High

808129

KCAB1
Voltage-gated potassium channel subunit beta-1

1

4

High-throughput

0.501

High

808133

TEAD2
Transcriptional enhancer factor TEF-4

1

2

High-throughput

0.501

High

808138

PKN2
Serine/threonine-protein kinase N2

1

16

High-throughput

0.501

High

808140

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

4

High-throughput

0.501

High

808143

SRSF7
Serine/arginine-rich splicing factor 7

1

16

High-throughput

0.501

High

808144

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

20

High-throughput

0.501

High

808145

MAPK3
MAP kinase-activated protein kinase 3

1

6

High-throughput

0.501

High

808152

CRTC2
CREB-regulated transcription coactivator 2

1

8

High-throughput

0.501

High

808153

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

1

High-throughput

0.501

High

808162

RHBD2
Rhomboid domain-containing protein 2

1

2

High-throughput

0.501

High

808164

PRP8
Pre-mRNA-processing-splicing factor 8

1

3

High-throughput

0.501

High

808170

AN13D
Ankyrin repeat domain-containing protein 13D

1

8

High-throughput

0.501

High

808171

TM1L2
TOM1-like protein 2

1

14

High-throughput

0.501

High

808172

MARK2
Serine/threonine-protein kinase MARK2

1

7

High-throughput

0.501

High

808173

DHX30
ATP-dependent RNA helicase DHX30

1

9

High-throughput

0.501

High

808178

LRAD3
Low-density lipoprotein receptor class A domain-containing protein 3

1

6

High-throughput

0.501

High

808181

SULF1
Extracellular sulfatase Sulf-1

1

1

High-throughput

0.501

High

808182

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

3

High-throughput

0.501

High

808184

MAML2
Mastermind-like protein 2

1

9

High-throughput

0.501

High

808192

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

1

6

High-throughput

0.501

High

808193

RGF1A
Ras-GEF domain-containing family member 1A

1

4

High-throughput

0.501

High

808200

RPGF6
Rap guanine nucleotide exchange factor 6

1

4

High-throughput

0.501

High

808201

GRK7
Rhodopsin kinase GRK7

1

13

High-throughput

0.501

High

808208

SMRC1
SWI/SNF complex subunit SMARCC1

1

9

High-throughput

0.501

High

808218

MOB3A
MOB kinase activator 3A

1

3

High-throughput

0.501

High

808220

TRI44
Tripartite motif-containing protein 44

1

3

High-throughput

0.501

High

808225

DCNL1
DCN1-like protein 1

1

1

Small-scale

0.501

High

808229

MARK4
MAP/microtubule affinity-regulating kinase 4

1

7

High-throughput

0.501

High

808233

RBM14
RNA-binding protein 14

1

8

High-throughput

0.501

High

808236

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

5

High-throughput

0.501

High

808247

PYM1
Partner of Y14 and mago

1

1

High-throughput

0.501

High

808251

KIFC3
Kinesin-like protein KIFC3

1

5

High-throughput

0.501

High

808256

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

8

High-throughput

0.501

High

808259

ASPC1
Tether containing UBX domain for GLUT4

1

1

High-throughput

0.501

High

808263

RNF38
E3 ubiquitin-protein ligase RNF38

1

5

High-throughput

0.501

High

808264

NSRP1
Nuclear speckle splicing regulatory protein 1

1

3

High-throughput

0.501

High

808268

CDIP1
Cell death-inducing p53-target protein 1

1

9

High-throughput

0.501

High

808269

P63
Tumor protein 63

1

15

High-throughput

0.501

High

808270

SRMS
Tyrosine-protein kinase Srms

1

14

High-throughput

0.501

High

808275

SP14L
Nuclear body protein SP140-like protein

1

9

High-throughput

0.501

High

808277

SGK2
Serine/threonine-protein kinase Sgk2

1

18

High-throughput

0.501

High

808284

DYRK4
Dual specificity tyrosine-phosphorylation-regulated kinase 4

1

8

High-throughput

0.501

High

808285

TULP4
Tubby-related protein 4

1

2

High-throughput

0.501

High

808288

FGF21
Fibroblast growth factor 21

1

4

High-throughput

0.501

High

808289

SAMN1
SAM domain-containing protein SAMSN-1

1

2

High-throughput

0.501

High

808297

PLK2
Serine/threonine-protein kinase PLK2

1

5

High-throughput

0.501

High

808301

TBCD7
TBC1 domain family member 7

1

1

High-throughput

0.501

High

808302

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

6

High-throughput

0.501

High

808304

STK26
Serine/threonine-protein kinase 26

1

20

High-throughput

0.501

High

808310

SEPT9
Septin-9

1

1

High-throughput

0.501

High

808311

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

8

High-throughput

0.501

High

808317

SYNP2
Synaptopodin-2

1

7

High-throughput

0.501

High

808319

FOXJ3
Forkhead box protein J3

1

5

High-throughput

0.501

High

808320

BAIP2
BAR/IMD domain-containing adapter protein 2

1

10

High-throughput

0.501

High

808321

AURKC
Aurora kinase C

1

9

High-throughput

0.501

High

808325

RUVB1
RuvB-like 1

1

6

High-throughput

0.501

High

808331

TR150
Thyroid hormone receptor-associated protein 3

1

10

High-throughput

0.501

High

808332

LC7L2
Putative RNA-binding protein Luc7-like 2

1

4

High-throughput

0.501

High

808337

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

20

High-throughput

0.501

High

808340

SCNAA
Sodium channel protein type 10 subunit alpha

1

20

High-throughput

0.501

High

808341

STK24
Serine/threonine-protein kinase 24

1

19

High-throughput

0.501

High

531754

PDIA4
Protein disulfide-isomerase A4

1

8

High-throughput

0.489

High

808089

IDD
Integral membrane protein DGCR2/IDD

1

10

High-throughput

0.489

High

808203

TM174
Transmembrane protein 174

1

2

High-throughput

0.489

High

808227

CYYR1
Cysteine and tyrosine-rich protein 1

1

1

High-throughput

0.489

High

808300

CALL5
Calmodulin-like protein 5

1

2

High-throughput

0.489

High

808308

SUN2
SUN domain-containing protein 2

1

1

High-throughput

0.489

High

808141

NFE2
Transcription factor NF-E2 45 kDa subunit

1

12

Small-scale

0.481

High

66534

CO062
Uncharacterized protein C15orf62, mitochondrial

1

0

High-throughput

0.480

High

313233

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

Small-scale

0.480

High

437184

MDR1
ATP-dependent translocase ABCB1

1

0

Small-scale

0.480

High

599553

SYT1
Synaptotagmin-1

1

0

High-throughput

0.480

High

808119

FCL
GDP-L-fucose synthase

1

0

High-throughput

0.480

High

808131

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.480

High

808188

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

0

High-throughput

0.480

High

808195

ERMIN
Ermin

1

0

High-throughput

0.480

High

808215

R51A1
RAD51-associated protein 1

1

0

High-throughput

0.480

High

808221

SAAL1
Protein SAAL1

1

0

High-throughput

0.480

High

808223

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.480

High

808307

S23A2
Solute carrier family 23 member 2

1

0

High-throughput

0.480

High

162492

XPO1
Exportin-1

1

9

Small-scale

0.479

High

165757

N4BP3
NEDD4-binding protein 3

1

8

Small-scale

0.479

High

165826

KDM6B
Lysine-specific demethylase 6B

1

7

Small-scale

0.479

High

167863

NPC1
NPC intracellular cholesterol transporter 1

1

13

High-throughput

0.479

High

178303

NMDE4
Glutamate receptor ionotropic, NMDA 2D

1

4

Small-scale

0.479

High

206944

SMAD6
Mothers against decapentaplegic homolog 6

1

20

Small-scale

0.479

High

208328

SPY1
Protein sprouty homolog 1

1

3

Small-scale

0.479

High

230124

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

1

Small-scale

0.479

High

232805

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

5

Small-scale

0.479

High

281982

ANXA9
Annexin A9

1

8

High-throughput

0.479

High

316818

KLF8
Krueppel-like factor 8

1

13

Small-scale

0.479

High

330904

PAK4
Serine/threonine-protein kinase PAK 4

1

9

Small-scale

0.479

High

445314

RSSA
Small ribosomal subunit protein uS2

1

5

Small-scale

0.479

High

503272

MTAP2
Microtubule-associated protein 2

1

12

High-throughput

0.479

High

507383

ERG
Transcriptional regulator ERG

1

4

Small-scale

0.479

High

521337

SKIL
Ski-like protein

1

4

Small-scale

0.479

High

540453

IL2RB
Interleukin-2 receptor subunit beta

1

4

Small-scale

0.479

High

552178

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

601170

VDAC1
Voltage-dependent anion-selective channel protein 1

1

5

Small-scale

0.479

High

609205

FGFR3
Fibroblast growth factor receptor 3

1

16

Small-scale

0.479

High

639692

IKBA
NF-kappa-B inhibitor alpha

1

6

Small-scale

0.479

High

646713

1433T
14-3-3 protein theta

1

20

Small-scale

0.479

High

650616

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

682255

IL2RG
Cytokine receptor common subunit gamma

1

5

Small-scale

0.479

High

683894

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

738509

TGFR1
TGF-beta receptor type-1

1

19

Small-scale

0.479

High

758149

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

Small-scale

0.479

High

778987

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

804164

NOTC1
Neurogenic locus notch homolog protein 1

1

13

Small-scale

0.479

High

808042

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.479

High

808043

KC1D
Casein kinase I isoform delta

1

4

Small-scale

0.479

High

808044

NRAM2
Natural resistance-associated macrophage protein 2

1

2

Small-scale

0.479

High

808046

ARRB1
Beta-arrestin-1

1

4

Small-scale

0.479

High

808053

KCNQ1
Potassium voltage-gated channel subfamily KQT member 1

1

10

Small-scale

0.479

High

808061

S12A3
Solute carrier family 12 member 3

1

2

Small-scale

0.479

High

808079

RBX1
E3 ubiquitin-protein ligase RBX1

1

3

Small-scale

0.479

High

808082

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.479

High

808114

GRB10
Growth factor receptor-bound protein 10

1

15

Small-scale

0.479

High

808117

CUL1
Cullin-1

1

5

Small-scale

0.479

High

808120

PTC1
Protein patched homolog 1

1

13

Small-scale

0.479

High

808126

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.479

High

808134

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.479

High

808137

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.479

High

808139

MK14
Mitogen-activated protein kinase 14

1

2

Small-scale

0.479

High

808147

KI26B
Kinesin-like protein KIF26B

1

10

Small-scale

0.479

High

808148

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

6

High-throughput

0.479

High

808150

S22A6
Solute carrier family 22 member 6

1

6

Small-scale

0.479

High

808157

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

Small-scale

0.479

High

808169

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

808194

GLIS3
Zinc finger protein GLIS3

1

4

Small-scale

0.479

High

808197

S22A8
Organic anion transporter 3

1

6

Small-scale

0.479

High

808202

PDC6I
Programmed cell death 6-interacting protein

1

10

Small-scale

0.479

High

808209

CUL5
Cullin-5

1

5

Small-scale

0.479

High

808230

FXL18
F-box/LRR-repeat protein 18

1

2

Small-scale

0.479

High

808266

ABCG4
ATP-binding cassette sub-family G member 4

1

2

Small-scale

0.479

High

808283

PDLI7
PDZ and LIM domain protein 7

1

9

Small-scale

0.479

High

808294

DDIT4
DNA damage-inducible transcript 4 protein

1

1

Small-scale

0.479

High

808298

GGA3
ADP-ribosylation factor-binding protein GGA3

1

16

Small-scale

0.479

High

808303

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

Small-scale

0.479

High

808318

MAGD2
Melanoma-associated antigen D2

1

7

High-throughput

0.479

High

808322

SCN8A
Sodium channel protein type 8 subunit alpha

1

20

Small-scale

0.479

High

808327

FBW1A
F-box/WD repeat-containing protein 1A

1

6

Small-scale

0.479

High

808339

TNR18
Tumor necrosis factor receptor superfamily member 18

1

2

Small-scale

0.479

High

173449

RER1
Protein RER1

1

0

Small-scale

0.458

High

204538

PROM1
Prominin-1

1

0

Small-scale

0.458

High

781265

AQP2
Aquaporin-2

1

0

Small-scale

0.458

High

808065

GSDMD
Gasdermin-D

1

0

Small-scale

0.458

High

808091

HSF1
Heat shock factor protein 1

1

0

Small-scale

0.458

High

808177

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

Small-scale

0.458

High

808191

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

808238

S38A3
Sodium-coupled neutral amino acid transporter 3

1

0

Small-scale

0.458

High

808255

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.458

High

808262

SC5A7
High affinity choline transporter 1

1

0

Small-scale

0.458

High

808154

LARGN
Protein Largen

1

2

High-throughput

0.457

High

808158

Q5TBB8
Lysosomal associated multispanning membrane protein 5, isoform CRA_a

1

7

Small-scale

0.457

High

808161

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

2

High-throughput

0.457

High

808180

TM139
Transmembrane protein 139

1

1

High-throughput

0.457

High

808189

MYCT1
Myc target protein 1

1

1

High-throughput

0.457

High

808190

TM252
Transmembrane protein 252

1

1

High-throughput

0.457

High

808246

RSLBB
Ras-like protein family member 11B

1

2

High-throughput

0.457

High

808253

STK31
Serine/threonine-protein kinase 31

1

1

High-throughput

0.457

High

808295

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

12

High-throughput

0.457

High

808101

RL18A
Large ribosomal subunit protein eL20

1

3

High-throughput

0.457

High

70543

HGB1A
Putative high mobility group protein B1-like 1

1

11

High-throughput

0.445

High

484077

CALM3
Calmodulin-3

1

3

High-throughput

0.445

High

808329

KDM2A
Lysine-specific demethylase 2A

1

13

Small-scale

0.437

High

808165

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

2

High-throughput

0.408

High

808199

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.408

High

808316

STRP2
Striatin-interacting protein 2

1

1

High-throughput

0.408

High

808051

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.391

High

808168

SHSA6
Protein shisa-6

2

0

High-throughput

0.316

High

277231

TUSC2
Tumor suppressor candidate 2

1

0

Small-scale

0.292

High

536326

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.279

Low

132429

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.261

Low

808156

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.261

Low

808159

RSH4A
Radial spoke head protein 4 homolog A

1

0

High-throughput

0.261

Low

808163

JHY
Jhy protein homolog

1

0

High-throughput

0.261

Low

808213

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

0

High-throughput

0.261

Low

808290

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.261

Low

808231

GUCD1
Protein GUCD1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024