Protein: LAP2A
Lamina-associated polypeptide 2, isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]

Gene: LAP2A, TMPO
Organism: Homo sapiens
Interactions: 69
UniProt ID: P42166

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005521 - lamin binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

385524

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

8

Small-scale

0.646

High

285606

BAF
Barrier-to-autointegration factor

1

1

Small-scale

0.618

High

837423

MAN1
Inner nuclear membrane protein Man1

1

4

High-throughput

0.618

High

837411

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

2

High-throughput

0.562

High

837410

NEK7
Serine/threonine-protein kinase Nek7

1

5

High-throughput

0.536

High

837400

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

2

Small-scale

0.504

High

559252

XRCC5
X-ray repair cross-complementing protein 5

1

2

Small-scale

0.479

High

837389

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.457

High

213852

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

High-throughput

0.445

High

344119

PTBP3
Polypyrimidine tract-binding protein 3

1

4

High-throughput

0.445

High

371383

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.445

High

400429

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.445

High

429460

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

442892

PRGR
Progesterone receptor

1

3

Small-scale

0.445

High

470901

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.445

High

484419

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

549295

SRF
Serum response factor

1

1

High-throughput

0.445

High

571568

IRF2
Interferon regulatory factor 2

1

1

High-throughput

0.445

High

732462

ARRB2
Beta-arrestin-2

1

3

High-throughput

0.445

High

765211

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.445

High

787916

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.445

High

837386

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.445

High

837387

ARRB1
Beta-arrestin-1

1

3

High-throughput

0.445

High

837390

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.445

High

837391

NEK3
Serine/threonine-protein kinase Nek3

1

4

High-throughput

0.445

High

837392

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.445

High

837394

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.445

High

837395

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

1

High-throughput

0.445

High

837399

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.445

High

837403

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

2

High-throughput

0.445

High

837413

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

837414

EYA1
Protein phosphatase EYA1

1

1

High-throughput

0.445

High

837416

SSBP3
Single-stranded DNA-binding protein 3

1

1

High-throughput

0.445

High

837417

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.445

High

837419

TF7L2
Transcription factor 7-like 2

1

5

High-throughput

0.445

High

837422

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.445

High

837425

MB212
Protein mab-21-like 2

1

1

High-throughput

0.445

High

48919

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

184601

MK13
Mitogen-activated protein kinase 13

1

0

Small-scale

0.426

High

335965

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.426

High

837420

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.426

High

837421

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

130021

PGRC1
Membrane-associated progesterone receptor component 1

1

2

High-throughput

0.407

High

271435

ATG13
Autophagy-related protein 13

1

1

High-throughput

0.407

High

417296

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

417988

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.407

High

439982

LCK
Tyrosine-protein kinase Lck

1

4

High-throughput

0.407

High

505137

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

1

High-throughput

0.407

High

619577

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.407

High

698455

CALX
Calnexin

1

2

High-throughput

0.407

High

813015

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.407

High

837388

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

High-throughput

0.407

High

837393

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

1

High-throughput

0.407

High

837396

CND2
Condensin complex subunit 2

1

1

High-throughput

0.407

High

837397

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

1

High-throughput

0.407

High

837398

RBP1
RalA-binding protein 1

1

2

High-throughput

0.407

High

837401

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.407

High

837402

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.407

High

837404

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

1

High-throughput

0.407

High

837405

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

1

High-throughput

0.407

High

837406

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.407

High

837407

ZNT7
Zinc transporter 7

1

1

High-throughput

0.407

High

837408

MSPD2
Motile sperm domain-containing protein 2

1

2

High-throughput

0.407

High

837409

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.407

High

837412

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.407

High

837415

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

4

High-throughput

0.407

High

837418

ENY2
Transcription and mRNA export factor ENY2

1

1

High-throughput

0.407

High

837424

EMC9
ER membrane protein complex subunit 9

1

2

High-throughput

0.407

High

388163

GLPA
Glycophorin-A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025