HitPredict

Interactor 1: ZBTB5 (O15062)
Zinc finger and BTB domain-containing protein 5
Gene: ZBTB5

Interactor 2: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19491398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 677 Hs			1 428
+	Hs
		166167 ZBTB5_HUMAN (1-662): 1.55e-134: 412: 100.00		HDAC1_HUMAN (3-385): 0: 588: 62.92
+	Hs
		177270 ZBT16_HUMAN (314-676): 3.62e-37: 149: 15.17		HDAC3_HUMAN (1-428): 0: 600: 100.00
+	Hs
		983971 ZBT16_HUMAN (314-676): 3.62e-37: 149: 15.17		HDAC1_HUMAN (3-385): 0: 588: 62.92
+	Mm
		140266 Q3UQ17_MOUSE (314-676): 6.98e-37: 148: 15.13		HDAC1_MOUSE (3-385): 0: 588: 62.92
+	Hs
		984006 ZBT16_HUMAN (314-676): 3.62e-37: 149: 15.17		HDAC2_HUMAN (3-422): 0: 580: 58.63
+	Hs
		177221 BCL6_HUMAN (119-571): 4.16e-23: 106: 7.91		HDAC3_HUMAN (1-428): 0: 600: 100.00
+	Mm
		140211 ZBT7A_MOUSE (585-674): 3.71e-25: 112: 31.58		HDAC1_MOUSE (3-385): 0: 588: 62.92
+	Hs
		781362 BCL6_HUMAN (119-571): 4.16e-23: 106: 7.91		HDAC1_HUMAN (3-385): 0: 588: 62.92
+	Hs
		177160 ZBT7A_HUMAN (3-124): 8.29e-19: 92.4: 43.44		HDAC3_HUMAN (1-428): 0: 600: 100.00
+	Hs
		781407 BCL6_HUMAN (119-571): 4.16e-23: 106: 7.91		HDAC2_HUMAN (3-422): 0: 580: 58.63
+	Hs
		312063 ZBT7A_HUMAN (3-124): 8.29e-19: 92.4: 43.44		HDAC1_HUMAN (3-385): 0: 588: 62.92
+	Mm
		1257439 ZBT7C_MOUSE (3-115): 7.07e-16: 83.2: 39.82		Q9JM08_MOUSE (1-428): 0: 595: 99.07
+	Hs
		1193248 ZSCA2_HUMAN (164-676): 8.9e-79: 264: 15.16		HDAC8_HUMAN (6-367): 8.28e-143: 414: 41.71
+	Hs
		312081 ZBT7A_HUMAN (3-124): 8.29e-19: 92.4: 43.44		HDAC2_HUMAN (3-422): 0: 580: 58.63
+	Hs
		1038838 ZBTB1_HUMAN (1-111): 2.43e-12: 72: 35.14		HDAC1_HUMAN (3-385): 0: 588: 62.92
+	Hs
		984038 ZBT16_HUMAN (314-676): 3.62e-37: 149: 15.17		HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24