HitPredict

Interactor 1: DCLK1 (O15075)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Interactor 2: GAB2 (Q9UQC2)
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100)
Gene: GAB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 676
+	Hs
		166574 DCLK1_HUMAN (1-740): 0: 896: 100.00		PKHA7_HUMAN (6-456): 1.7e-80: 278: 14.62
+	Hs
		682077 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		GAB2_HUMAN (1-676): 0: 763: 100.00
+	Hs
		1035399 M3K3_HUMAN (51-646): 5.47e-139: 424: 18.59		GAB1_HUMAN (3-675): 0: 652: 37.36
+	Hs
		681831 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		GAB1_HUMAN (3-675): 0: 652: 37.36
+	Hs
		166613 DCLK1_HUMAN (1-740): 0: 896: 100.00		PKHA5_HUMAN (6-453): 3.24e-26: 117: 15.35
+	Hs
		166581 DCLK1_HUMAN (1-740): 0: 896: 100.00		PHLB2_HUMAN (9-114): 2.45e-24: 111: 28.04
+	Hs
		1039174 KCC2D_HUMAN (385-737): 1.46e-130: 398: 33.05		MYO10_HUMAN (3-153): 1.44e-34: 143: 24.05
+	Hs
		208297 DCX_HUMAN (6-345): 2.97e-136: 407: 72.13		PKHA5_HUMAN (6-453): 3.24e-26: 117: 15.35
+	Hs
		1039033 KCC2G_HUMAN (387-647): 2.94e-63: 223: 43.77		MYO10_HUMAN (3-153): 1.44e-34: 143: 24.05
+	Hs
		1334862 KCC2A_HUMAN (387-648): 1.19e-64: 224: 42.48		PKHA5_HUMAN (6-453): 3.24e-26: 117: 15.35