HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: K1C18 (P05783)
Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)
Gene: KRT18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0034451 - centriolar satellite
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2479 Hs			1 430
+	Hs
		166661 CE290_HUMAN (1-2479): 0: 650: 100.00		K1C19_HUMAN (79-389): 5.66e-89: 277: 50.64
+	Mm
		1149149 CE290_MOUSE (1-2451): 0: 628: 87.07		K2C5_MOUSE (45-400): 4.75e-71: 236: 25.42
+	Hs
		359355 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		K1C14_HUMAN (77-428): 5.85e-89: 279: 49.58
+	Hs
		444372 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		K1C19_HUMAN (79-389): 5.66e-89: 277: 50.64
+	Hs
		445052 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		K1C16_HUMAN (77-404): 2.34e-87: 275: 49.85
+	Hs
		522534 MYH1_HUMAN (1-813): 5.08e-33: 143: 11.14		K1C13_HUMAN (57-389): 1.38e-85: 270: 48.96
+	Hs
		49550 MYH1_HUMAN (1-813): 5.08e-33: 143: 11.14		A1A4E9_HUMAN (57-389): 3.41e-85: 269: 48.66
+	Hs
		280584 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		KRT34_HUMAN (79-385): 1.5e-82: 260: 44.81
+	Hs
		821662 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		K2C6C_HUMAN (45-406): 3.96e-73: 241: 24.18
+	Hs
		408811 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		K1C18_HUMAN (1-430): 1.32e-72: 236: 100.00
+	Hs
		444307 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		K1C19_HUMAN (79-389): 5.66e-89: 277: 50.64
+	Hs
		444464 AKAP9_HUMAN (83-717): 1.65e-12: 75.8: 10.19		K1C19_HUMAN (79-389): 5.66e-89: 277: 50.64
+	Hs
		551676 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		K1C17_HUMAN (58-420): 5.11e-86: 270: 48.08
+	Hs
		974058 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		K1C17_HUMAN (58-420): 5.11e-86: 270: 48.08
+	Hs
		725143 MYH10_HUMAN (1915-2469): 2.86e-09: 65.2: 14.34		K1C17_HUMAN (58-420): 5.11e-86: 270: 48.08
+	Hs
		531529 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		K2C5_HUMAN (45-400): 2.97e-73: 242: 25.70
+	Hs
		359462 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		K2C6A_HUMAN (45-406): 1.72e-71: 236: 23.90
+	Hs
		408726 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		K1C18_HUMAN (1-430): 1.32e-72: 236: 100.00