HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 2090
+	Hs
		969605 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		NIN_HUMAN (1-2090): 0: 617: 100.00
+	Hs
		1233437 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		NIN_HUMAN (1-2090): 0: 617: 100.00
+	Hs
		166640 CE290_HUMAN (1-2479): 0: 650: 100.00		CE290_HUMAN (1326-2090): 1.25e-17: 92.4: 9.75
+	Mm
		1142079 CE290_MOUSE (1-2451): 0: 628: 87.07		NIN_MOUSE (29-1133): 9.22e-18: 92.8: 10.82
+	Hs
		166801 CE290_HUMAN (1-2479): 0: 650: 100.00		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Hs
		828575 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		CENPF_HUMAN (29-810): 8.47e-25: 116: 11.38
+	Hs
		969580 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		CENPE_HUMAN (1236-2090): 8.51e-24: 112: 11.72
+	Hs
		969621 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Zm
		5443 A0A1D6DZK4_MAIZE (2-1110): 4e-47: 189: 11.12		A0A1D6DZK4_MAIZE (30-793): 4.02e-19: 97.4: 11.01
+	Hs
		1034574 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		GOGA4_HUMAN (2-1081): 4.23e-31: 136: 12.36
+	Hs
		724839 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55
+	Mm
		93578 PLEC_MOUSE (2-1228): 1.06e-38: 162: 9.59		DESP_MOUSE (1003-2071): 1e-14: 82.8: 11.96
+	Hs
		724994 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55
+	Hs
		1034577 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		GOGB1_HUMAN (1228-2090): 3.18e-16: 87.7: 10.60
+	Hs
		1068536 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		PLEC_HUMAN (320-1163): 1.13e-15: 86.3: 13.21
+	Hs
		502933 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH4_HUMAN (1282-2050): 5.42e-19: 96.7: 12.82
+	Hs
		502901 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH6_HUMAN (1342-2059): 1.88e-14: 82.1: 13.91
+	Hs
		1068617 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MY18A_HUMAN (1488-2028): 1.65e-10: 69: 18.93
+	Hs
		522585 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH7_HUMAN (127-785): 5.86e-14: 80.4: 12.17
+	Hs
		1313555 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93