HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: CSF2R (P15509)
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CDw116) (CD antigen CD116)
Gene: CSF2RA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	12637324
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 400
+	Hs
		158387 IKKB_HUMAN (1-743): 0: 583: 50.87		CSF2R_HUMAN (11-400): 7.14e-93: 286: 100.00
+	Hs
		167480 IKKA_HUMAN (1-745): 0: 588: 100.00		EPHA3_HUMAN (7-321): 2.01e-44: 166: 9.88
+	Hs
		158410 IKKB_HUMAN (1-743): 0: 583: 50.87		IL3RB_HUMAN (122-320): 1.39e-10: 65.2: 13.89
+	Mm
		69649 IKKA_MOUSE (1-745): 0: 573: 95.44		PTPRS_MOUSE (2-374): 2.9e-10: 64.4: 9.44
+	Hs
		1056244 SIK2_HUMAN (7-731): 2.17e-125: 398: 15.52		I13R2_HUMAN (1-357): 3.77e-48: 169: 14.58
+	Hs
		616987 MARK2_HUMAN (12-724): 1.19e-142: 439: 15.92		PTPRD_HUMAN (2-375): 8.19e-23: 102: 9.82
+	Hs
		617030 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		PTPRD_HUMAN (2-375): 8.19e-23: 102: 9.82
+	Hs
		254437 ROCK2_HUMAN (10-739): 5.13e-122: 399: 16.40		PTPRF_HUMAN (1-324): 2.74e-13: 74.1: 10.00
+	Hs
		625528 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TITIN_HUMAN (1-214): 2.04e-10: 65.2: 12.00
+	Hs
		647831 MARK3_HUMAN (13-221): 1.13e-24: 112: 35.05		EPHB2_HUMAN (7-349): 8.18e-47: 173: 10.70