HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 616
+	Hs
		652533 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		625131 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		270375 KS6A5_HUMAN (1-314): 1.41e-86: 292: 22.05		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		568552 KAPCA_HUMAN (3-316): 7.79e-90: 287: 27.41		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		647830 MARK3_HUMAN (13-221): 1.13e-24: 112: 35.05		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Zm
		2187 A0A0B4J3D8_MAIZE (14-440): 8.89e-112: 348: 19.73		A0A1D6EZA2_MAIZE (83-505): 1.89e-78: 267: 14.57