HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~U1snRNP70_N
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 437
+	Sp
		143353 RSMB_SCHPO (6-75): 1.7e-23: 90.4: 30.77		RU17_SCHPO (1-277): 2.14e-51: 175: 38.27
+	Hs
		927963 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		442037 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		912052 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		538978 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Sp
		143345 RUXG_SCHPO (4-79): 8.96e-22: 83.9: 26.32		RU17_SCHPO (1-277): 2.14e-51: 175: 38.27
+	Hs
		442013 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		441858 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Sc
		766941 RSMB_YEAST (7-118): 6.9e-23: 90.4: 22.14		RU17_YEAST (3-297): 9.1e-46: 162: 26.58
+	Hs
		68425 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		68395 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Sc
		770323 RUXG_YEAST (4-78): 1.97e-21: 83.1: 31.17		RU17_YEAST (3-297): 9.1e-46: 162: 26.58
+	Sc
		376834 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Sc
		376799 RSMB_YEAST (7-118): 6.9e-23: 90.4: 22.14		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Mm
		646096 RSMB_MOUSE (6-86): 1.3e-23: 93.1: 23.86		TIA1_MOUSE (3-246): 4.89e-27: 113: 13.42
+	Sc
		376893 LSM3_YEAST (4-87): 7.53e-21: 81.9: 23.60		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Hs
		538845 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26
+	Hs
		235690 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55