HitPredict

Interactor 1: FYB1 (O15117)
FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein)
Gene: FYB1

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 126
+	Hs
		1087196 NIPBL_HUMAN (74-755): 2.54e-62: 230: 11.11		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918442 NIPBL_HUMAN (74-755): 2.54e-62: 230: 11.11		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1274409 ASPP1_HUMAN (7-477): 1.69e-24: 112: 16.57		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		1056847 MDC1_HUMAN (16-730): 7.54e-15: 81.2: 9.50		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1056919 MDC1_HUMAN (16-730): 7.54e-15: 81.2: 9.50		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		918364 MDC1_HUMAN (16-730): 7.54e-15: 81.2: 9.50		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707631 MDC1_HUMAN (16-730): 7.54e-15: 81.2: 9.50		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		1087338 CHAP1_HUMAN (239-725): 1.33e-12: 73.5: 11.85		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918607 CHAP1_HUMAN (239-725): 1.33e-12: 73.5: 11.85		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707710 CHAP1_HUMAN (239-725): 1.33e-12: 73.5: 11.85		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		1129830 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		617962 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21
+	Hs
		1087299 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1264778 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		883041 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83
+	Hs
		918561 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241595 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		886166 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		1264792 TITIN_HUMAN (311-745): 7.86e-09: 61.9: 12.22		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62